README.md

In igordot/copynumber: Segmentation of single- and multi-track copy number data by penalized least squares regression (with hg38 and mm10).

copynumber with hg38 and mm10

This is an updated version of the copynumber R package. It has been modified to support the human hg38 and mouse mm10 genome builds. Speicifically, this is used for the assembly parameter in aspcf, multipcf, pcf, and winsorize functions.

You can install this version of the package from GitHub using:

BiocManager::install("igordot/copynumber")

This modification builds upon the previous work of aroneklund and ShixiangWang. There is a fork by Irrationone that provides a species-agnostic approach, but the enhanced functionality adds a new parameter that makes it not backward compatible. Any packages that depend on copynumber (such as sequenza, PureCN, or scarHRD) would need to be modified as well to take advantage of the new feature.

This fork is based on copynumber 1.29.0 (part of Bioconductor 3.12). The specific version is likely not relevant for most applications as there have been no changes to the code since 2013.

igordot/copynumber documentation built on Sept. 18, 2020, 8:48 a.m.