ci_loa_bt: Confidence intervals for limits of agreement (using...

In ikoenemund/blandxtr: Advanced Bland Altman analysis for method comparison

Description

ci_loa_bt returns confidence intervals (CI) for limits of agreement (LoA). Calculation is based on parametric bootstrap-t.

Usage

ci_loa_bt(bt, input_dt, bias_alt, loa_l, loa_u, var_loa, alpha, beta, n,
  n_obs, d, d_a, bsv, wsv)

Arguments

bt	number of bootstrap samples
input_dt	data.table with input dataset
bias_alt	set TRUE for alternative calculation of bias (small within-subject variance) and its variance, set FALSE for standard calculation of bias (small between-subjects variance) and its variance
loa_l	lower limit of agreement
loa_u	upper limit of agreement
var_loa	variance of limits of agreement
alpha	for 100*(1-alpha)%-confidence interval around LoA
beta	for 100*(1-beta)%-confidence interval around bias
n	number of subjects
n_obs	number of observations
d	mean of all differences
d_a	modified mean of all differences
bsv	between-subjects variance
wsv	within-subject variance

Value

A list with the following elements is returned

• ci_l_loa_l_bt lower limit of 95%-CI for lower LoA

• ci_u_loa_l_bt upper limit of 95%-CI for lower LoA

• ci_l_loa_u_bt lower limit of 95%-CI for upper LoA

• ci_u_loa_u_bt upper limit of 95%-CI for upper LoA

Note

For further information please see:

• Efron, B. and Tibshirani, R. J., An introduction to the bootstrap. Monographs on statistics and applied probability, 57, 1993.

• Carpenter, J. and Bithell, J., Bootstrap confidence intervals: when, which, what? A practical guide for medical statisticians. Statistics in medicine, 19 (9), 2000.

Author(s)

Inga Koenemund [e-mail]

ikoenemund/blandxtr documentation built on June 13, 2019, 8:53 p.m.