IDOLOptimizedCpGs: IDOL Optimized CpGs for adult blood DNA methylation...

IDOLOptimizedCpGsR Documentation

IDOL Optimized CpGs for adult blood DNA methylation deconvolution EPIC

Description

This object is a vector of length 450 consisting of the names of the IDOL optimized CpGs. These CpGs are used as the backbone for deconvolution and were selected because their methylation signature differs across the six normal leukocyte subtypes.

Usage

IDOLOptimizedCpGs

Format

An object of class "character" of length 450.

The format is: chr [1:450] "cg08769189" "cg07661835" "cg00219921" "cg13468685" ...

References

LA Salas et al. (2018). An optimized library for reference-based deconvolution of whole-blood biospecimens assayed using the Illumina HumanMethylationEPIC BeadArray. Genome Biology 19, 64. doi: 10.1186/s13059-018-1448-7

DC Koestler et al. (2016). Improving cell mixture deconvolution by identifying optimal DNA methylation libraries (IDOL). BMC bioinformatics. 17, 120. doi: 10.1186/s13059-018-1448-7.

Examples

# Do not run
# head(IDOLOptimizedCpGs)

immunomethylomics/FlowSorted.Blood.EPIC documentation built on May 24, 2023, 2:22 a.m.