IDOLOptimizedCpGsBloodExtended450k: IDOL Optimized CpGs for extended blood DNA methylation...
In immunomethylomics/FlowSorted.BloodExtended.EPIC: Illumina EPIC data on extended immunomagnetic sorted blood populations
IDOLOptimizedCpGsBloodExtended450k R Documentation
IDOL Optimized CpGs for extended blood DNA methylation deconvolution
450k
Description
This object is a vector of length 1500 consisting of the names of the
IDOL optimized CpGs. These CpGs are used as the backbone for
deconvolution with 450k and were selected because their methylation
signature differs across the twelve normal leukocyte subtypes.
Usage
IDOLOptimizedCpGsBloodExtended450k
Format
An object of class "character" of length 1200.
The format is:
chr [1:1500] "cg18857618" "cg00644351" "cg09177577" "cg21091766" ...
References
LA Salas et al. (2021). Enhanced cell deconvolution of
peripheral blood using DNA methylation for high-resolution immune profiling.
(Under review)
LA Salas et al. (2018). An optimized library for
reference-based deconvolution of whole-blood biospecimens assayed using the
Illumina HumanMethylationEPIC BeadArray. Genome Biology 19, 64. doi:
10.1186/s13059-018-1448-7
DC Koestler et al. (2016). Improving cell mixture
deconvolution by identifying optimal DNA methylation libraries (IDOL).
BMC bioinformatics. 17, 120. doi:
10.1186/s13059-018-1448-7.
Examples
# Do not run
# data("IDOLOptimizedCpGsBloodExtended450k")
immunomethylomics/FlowSorted.BloodExtended.EPIC documentation built on Jan. 29, 2024, 8:43 p.m.
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| IDOLOptimizedCpGsBloodExtended450k | R Documentation |
IDOL Optimized CpGs for extended blood DNA methylation deconvolution 450k
Description
This object is a vector of length 1500 consisting of the names of the IDOL optimized CpGs. These CpGs are used as the backbone for deconvolution with 450k and were selected because their methylation signature differs across the twelve normal leukocyte subtypes.
Usage
IDOLOptimizedCpGsBloodExtended450k
Format
An object of class "character" of length 1200.
The format is: chr [1:1500] "cg18857618" "cg00644351" "cg09177577" "cg21091766" ...
References
LA Salas et al. (2021). Enhanced cell deconvolution of peripheral blood using DNA methylation for high-resolution immune profiling. (Under review)
LA Salas et al. (2018). An optimized library for reference-based deconvolution of whole-blood biospecimens assayed using the Illumina HumanMethylationEPIC BeadArray. Genome Biology 19, 64. doi: 10.1186/s13059-018-1448-7
DC Koestler et al. (2016). Improving cell mixture deconvolution by identifying optimal DNA methylation libraries (IDOL). BMC bioinformatics. 17, 120. doi: 10.1186/s13059-018-1448-7.
Examples
# Do not run
# data("IDOLOptimizedCpGsBloodExtended450k")
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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