isarnassiri/CMEA: CMEA: An R package for Systematic Exploration of Single-Cell Morphological Phenotypes from Transcriptomic Profile

CMEA is a tool for cell morphology enrichment analysis and link transcriptomic alterations with cell morphological phenotypes. In our approach we (1) map the transcriptomic profile of a query against the L1000 LINCS repository, (2) create a gene set repository for cell morphological features (CM), (3) identify the top CMs associated with alterations and analyze their direction of regulation, and (4) model a regulatory network of cell morphological phenotypes.

Getting started

Package details

AuthorIsar Nassiri, Matthew McCall
Bioconductor views Regression Software StatisticalMethod
MaintainerIsar Nassiri <>
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
isarnassiri/CMEA documentation built on May 18, 2021, 4:42 a.m.