iweir/metaRMST: Meta-Analysis of RMSTD

R implementation of a multivariate meta-analysis of randomized controlled trials (RCT) with the difference in restricted mean survival times (RMSTD). Use this package with individual patient level data from an RCT for a time-to-event outcome to determine combined effect estimates according to 4 methods: 1) a univariate meta-analysis using observed treatment effects, 2) a univariate meta-analysis using effects predicted by fitted Royston-Parmar flexible parametric models, 3) multivariate meta-analysis with analytically derived covariance, 4) multivariate meta-analysis with bootstrap derived covariance. This package computes all combined effects and provides an RMSTD curve with combined effect estimates and their confidence intervals.

Getting started

Package details

AuthorIsabelle Weir [aut, cre], Lu Tian [aut], Ludovic Trinquart [aut]
MaintainerIsabelle Weir <[email protected]>
LicenseGPL-2
Version1.0.0
URL https://github.com/iweir/metaRMST
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
install.packages("remotes")
remotes::install_github("iweir/metaRMST")
iweir/metaRMST documentation built on July 11, 2019, 6:06 p.m.