SQANTI Explorer provides several data exploration utlities to allow you to explore the isoform classifications provided by SQANTI (SQANTI paper). SQANTI Explorer provides live filtering of isoforms, multiple graphs, and an integrated genome browser with IGV. Furthermore, SQANTI Explorer allows for inter-sample analysis with multi-sample graphs and multi-track genome browsing. If you wish to perform inter-species analysis, SQANTI Explorer provides built-in liftOver support with UCSC liftOver.
If you are viewing this from SQANTI Explorer already, you can skip this section.
SQANTI Explorer is a Shiny app and is distributed as a Docker image.
docker pull jcbwndsr/sqantiexplorer
(you may need to run with sudo)docker run -it -p 3838:80 jcbwndsr/sqantiexplorer
The filters panel in the sidebar allows you to filter your datasets by certain criteria. By ticking each checkbox, the isoforms in each of your datasets will be dynamically filtered.
The plots tab provides many graphs to explore your filtered data. All graphs except the summary graph will be updated each time you select filters from the filters panel; the summary graph displays a summary of the unfiltered datasets. Clicking on the different regions of the graphs will update the count in the "Selected Transcripts" box. You can download your data with the download buttons:
The genome browser tab allows you to explore the transcripts in your filtered datasets with IGV. You can view datasets with the same genome side-by-side. Below are instructions for using the genome browser.
If you find a bug that you would like fixed or have a feature request, please submit an issue at the issue tracker.
This project has been developed as part of the minor project for the BIST MMRES.
Thanks to Julien Lagarde (CRG), David Alejandro Juan SopeƱa (UPF), and Luis Jose Ferrandez Peral (UPF) for their mentorship.
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