This is an R package developed to integrate analysis of multiple types of molecular profiling data (transcriptomics, proteomics, metabolomics, and epigenomics). It loads and deduplicates data, converts identifiers, performs enrichment/overrepresentation analysis on individual datasets, and combines these analyses with rank aggregation. There are multiple options for each step.
This software depends on the following R packages:
From CRAN:
igraph
httr
RankAggreg
RobustRankAggreg
From BioConductor:
org.Mm.eg.db
AnnotationDbi
EnrichmentBrowser
rWikiPathways
PGSEA
It comes bundled with GSEA_4.0.3 and JDK11 for running GSEA.
To install:
git clone https://github.com/jamieobrett/multiomics.git
Then open R
devtools::document(pkg="path/to/multiomics")
devtools::install(pkg="path/to/multiomics")
library(multiomics)
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