This analysis allows users to compute effect sizes based on the design and measurement of the studies. In case multiple types of designs and measurements are included in the data set, the user can specify the order in which the effect sizes are calculated (the effect size from the following option is filled in only if it was computed in the previous step).
Already included effect sizes can be passed forward using the Reported effect sizes option.
The selected effect size can be computed only for a subset of the dataset using the Subset indicator variable..
See metafor's documentation for more detail about the effect sizes.
The design dropdown allows users to select the type of effect size based on the design of the original studies.
The measurement dropdown allows users to select the type effect size based on the measurement in the original studies.
The available measurement options depend on the selected design type: - Independent groups: Quantitative / Binary / Counts per time / Mixed - Variable association: Quantitative / Binary / Mixed - Single group: Quantitative / Binary / Counts per time - Repeated measures/matched groups: Quantitative / Binary
The measurement dropdown is enabled only when a design type other than "Other" is selected.
The Effect size dropdown allows users to select the specific effect size or outcome measure to be calculated based on the chosen design and measurement type. The available options are dynamically adjusted according to the selected design and measurement type.
For SMD (including D2ORN, D2ORL) the Cohen's d, T-Statistics from an independent samples t-test, or (signed) P-Values together with the group sizes are sufficient statistics.
For Binary designs (and the corresponding Mixed designs) the table frequencies (Group 1/Outcome +, Group 1/Outcome -, Group 2/Outcome +, and Group 2/Outcome -) or the first column (Group 1/Outcome + and Group 2/Outcome +) with sample sizes (Sample Size Group 1 and Sample Size Group 2) are sufficient statistics.
The Binary design uses the corresponding table: | | Outcome + | Outcome - | Sample Size | | :--- | :----: | :----: | ---: | | Group 1 | Group 1/Outcome + | Group 1/Outcome - | Sample Size Group 1 | | Group 2 | Group 2/Outcome + | Group 2/Outcome - | Sample Size Group 2 |
For PHI, ZPHI, RPB, and ZPB the Sampling Variance Type specifies ST = stratified vs CS = cross-sectional design, the Mixed option allows passing of character vector specifying ST/CS for each study.
For Binary designs the table frequencies (Outcome +/+, Outcome +/-, Outcome -/+, and Outcome -/-) or the first column (Outcome +/+ and Outcome -/+) with the total +/. and -/. outcomes (Outcome +/+ and Outcome +/-, and Outcome -/+ and Outcome -/-) are sufficient statistics.
For RPB, RBIS, ZPB, and ZBIS the Cohen's d, T-Statistics from an independent samples t-test, or (signed) P-Values together with the group sizes are sufficient statistics.
The Binary design uses the corresponding table: | | Variable 2, Outcome + | Variable 2, Outcome + | Sample Size | | :--- | :----: | :----: | ---: | | Variable 1, Outcome + | Outcome +/+ | Outcome +/- | Outcome +/+ and +/- | | Variable 1, Outcome - | Outcome -/+ | Outcome -/- | Outcome -/+ and -/- |
For Binary designs the Events and Sample Size or the Events and Non-Events are sufficient statistics.
Correlation refers to between measures or between groups correlation.
For SMCC the Cohen's d, T-Statistics from paired-samples t-test, or (signed) P-Values together with the group sizes and correlation are sufficient statistics.
The Binary design uses the corresponding table (Time can reffer to different treatments or matched groups): | | Time 2, Outcome + | Time 2, Outcome + | | :--- | :----: | ---: | | Time 1, Outcome + | Outcome +/+ | Outcome +/- | | Time 1, Outcome - | Outcome -/+ | Outcome -/- |
The Binary design can be also reported marginally which results in the following table: | | Outcome + | Outcome - | | :--- | :----: | ---: | | Time 1 | Time 1/Outcome + | Time 1/Outcome - | | Time 2 | Time 2/Outcome + | Time 2/Outcome - |
In the Binary Marginal design the user also has to supply either the Correlation or Proportion of +/+ outcomes in the binary design. If an impossible value is supplied (the correlation/proportion is restricted by the possible binary tables) the effect size is not calculated.
Note that (Semi)Partial Correlation in the input does NOT correspond to the raw correlation between the variables. The input can be used when e.g., the partial eta2 is known.
For Partial and Semi-Partial Correlations the P-Value can be supplied instead of the T-Statistic.
For Model fit only one of the R-Squared, F-Statistic, and P-Value is required.
The specific variable inputs are based on selected effect sizes.
Note that users can supply "signed" P-Value (e.g., p = -0.01, 0.95) where the sign determines the sign of the resulting effect size (p = -0.01 leads to a negative effect size and p = 0.95 leads to a positive effect size). Sign of T-Statistics is used in the same manner.
Cohen's d: Already reported Cohen's d (for SMD only).
Binary Measurement
Sample Size Group 2: Total sample size of Group 2.
Counts Per Time Measurement
Events Group 2: Number of events in Group 2.
Mixed Measurement
P-Value: P-values for the correlation coefficients.
Binary Measurement
Sample Size: Total sample sizes.
Binary Measurement
Sample Size: Total sample sizes.
Counts Per Time Measurement
Sample Size: Total sample sizes.
Binary Measurement
Sample Size: Total sample sizes.
Partial and Semi-Partial Correlations
(Semi)Partial Correlation: Semi(partial) correlations of the regression coefficient.
Model fit
P-Value: P-values for the F-test of regression coefficients.
Relative Excess Heterozygosity (REH)
Available only for:
- Independent groups design with Binary measurement.
- Independent groups design with Counts per time measurement.
- Independent groups design with Mixed measurement and effect sizes PBIT
, OR2DN
, or OR2DL
.
- Variable association with Binary measurement.
- Single group designs with Binary measurement.
- Single group designs with Counts per time measurement.
The Add input field allows you to specify a small constant to add to zero cells, counts, or frequencies when computing effect sizes, as many effect sizes are undefined when one of the cells, counts or frequencies is equal to zero.
Default Value: - 0.5: Default value for most effect sizes. - 0: Used for AS, PHI, ZPHI, RTET, ZTET, IRSD, PAS, PFT, IRS, IRFT
The To dropdown allows you to specify when the values under the Add option should be added to
Options - All: The value of Add is added to each cell/count/frequency of all studies. - Only zero: The value of Add is added to each cell/count/frequency of a study with at least one cell/count/frequency equal to 0. - If any zero: The value of Add is added to each cell/count/frequency of all studies, but only when there is at least one study with a zero cell/count/frequency. - None: No adjustment to the observed table frequencies is made.
The Drop Studies with No Cases/Events
radio button group allows you to specify whether studies with no cases or events should be dropped when calculating the effect sizes.
Options: - Yes: Drop studies with no cases/events. - No: Do not drop studies with no cases/events.
The Sampling variance type dropdown allows you to specify the type of sampling variances for the effect size. The options available depend on the design, measurement, and effect size values.
Options: - LS: Large-sample approximation. - LS2: Alternative large-sample approximation. - UB: Unbiased estimates of the sampling variances. - AV: Sampling variances with the sample-size weighted average. - HO: Homoscedastic variances assumption. - AVHO: Homoscedasticity variances assumption for both groups across studies.
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