assessSignatures: Main function for fitting signatures by group with confidence...

Description Usage Arguments

Description

Main function for fitting signatures by group with confidence intervals.

Usage

1
2
assessSignatures(DNMs, cancer_signatures = cancer_signatures,
  group = "parent", rnd.seed = 1234, n = 1000)

Arguments

DNMs

A data.frame that contains information about the mutations. Necessary columns are surrounding, substitution plus a column with information about the groups.

cancer_signatures

A matrix with relative abundances of all 96 mutation types in the rows and all signatures to be investigated in the columns.

group

Name of the column in DNMs to base the groups upon.

rnd.seed

Random seed to involve in the resampling of the fitting.

n

Number of resamplings to be done.


jgoldmann/MutSigs documentation built on May 29, 2019, 8:01 a.m.