read_geo_tsv: Parse tab-delimited methylation matrices often found in GEO...

Description Usage Arguments Value References Examples

Description

This is meant to parse the uncompressed Series Matrix files when IDATs are not available. A CSV sample sheet of the same format required by read_idat should still be provided to annotate Sample_Group for analysis, otherwise you will only be able to generate PCA plots.

Usage

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read_geo_tsv(tsv_beta_matrix_file, csv_sample_sheet_file = NULL)

Arguments

tsv_beta_matrix_file

Path to the GEO text file

csv_sample_sheet_file

Path to the sample sheet for annotations. Optional

Value

parsed minfi GenomicRatioSet

References

Prickett AR, Ishida M, Böhm S, Frost JM et al. Genome-wide methylation analysis in Silver-Russell syndrome patients. Hum Genet 2015 Mar;134(3):317-332. PMID: 25563730

Examples

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## Not run: 
grset <- read_geo_tsv("extdata/GSE55491/GSE55491_series_matrix.txt")

## End(Not run)

kevinlul/EpigeneLite documentation built on Dec. 21, 2021, 6:35 a.m.