Adaptive Optimal Two-Stage Designs in R

adoptr | Adaptive Optimal Two-Stage Designs |

AffineScore-class | Affine functions of scores |

AverageN2-class | Regularization via L1 norm |

boundary-designs | Boundary designs |

bounds | Get support of a prior or data distribution |

condition | Condition a prior on an interval |

ConditionalPower-class | Conditional power of a design given stage-one outcome |

ConditionalSampleSize-class | Conditional sample size of a design given stage-one outcome |

ConditionalScore-class | Class for conditional scoring function |

Constraint-class | Formulating constraints |

ConstraintsCollection-class | Collection of constraints |

ContinuousPrior-class | Continuous univariate prior distributions |

critical-values | Query critical values of a design |

cumulative_distribution_function | Cumulative distribution function |

DataDistribution-class | Data distributions |

evaluate | Evaluation of a score |

expectation | Expected value of a function |

expected | Compute the expectation of a conditional score |

GroupSequentialDesign-class | Group-sequential two-stage designs |

IntegralScore-class | Unconditional score class obtained by integration of a... |

make_tunable | Fix parameters during optimization |

minimize | Find optimal two-stage design by constraint minimization |

n | Query sample size of a design |

N1-class | Regularize n1 |

NormalDataDistribution-class | Normal data distribution |

OneStageDesign-class | One-stage designs |

plot-TwoStageDesign-method | Plot 'TwoStageDesign' with optional set of conditional scores |

PointMassPrior-class | Univariate discrete point mass priors |

posterior | Compute posterior distribution |

predictive_cdf | Predictive CDF |

predictive_pdf | Predictive PDF |

Prior-class | Univariate prior on model parameter |

probability_density_function | Probability density function |

score-arithmetic | Score arithmetic |

simulate-TwoStageDesign-numeric-method | Draw samples from a two-stage design |

subject_to | Create a collection of constraints |

tunable_parameters | Switch between numeric and S4 class representation of a... |

TwoStageDesign-class | Two-stage designs |

UnconditionalScore-class | Class for unconditional scoring function |

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