This package allows users to estimate the sciencewise false discovery rate from Jager and Leek, "Empirical estimates suggest most published medical research is true," 2013, Biostatistics, using an EM approach due to the presence of rounding and censoring. It also allows users to estimate the proportion of true null hypotheses in the presence of covariates, using a regression framework, as per Boca and Leek, "A regression framework for the proportion of true null hypotheses," 2015, bioRxiv preprint.
Package details 


Author  Jeffrey T. Leek, Leah Jager, Simina M. Boca 
Bioconductor views  MultipleComparison Software StatisticalMethod 
Maintainer  Simina M. Boca <[email protected]>, Jeffrey T. Leek <[email protected]> 
License  GPL (>= 3) 
Version  1.2.1 
Package repository  View on GitHub 
Installation 
Install the latest version of this package by entering the following in R:

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