SKAT is an R-package for gene/region-based multiple variant tests. It has functions for Burden test, SKAT, and SKAT-O with adjusting for covariates and kinship.
Following are main functions and key references. For details, please refer the package manual and vignettes.
SKAT function: Burden test, SKAT, and SKAT-O
Robust approaches functions for binary traits: SKATBinary_Robust and SKAT_CommonRare_Robust
Zhao, Z., Bi, W., Zhou, W., VanderHaar, P., Fritsche, L.G., Lee, S. (2020) UK Biobank Whole-Exome Sequence Binary Phenome Analysis with Robust Region-based Rare-Variant Test. AJHG, 2020, 3-12.
SKATBinary function: Burden test, SKAT, and SKAT-O with efficient resampling for binary traits
SKAT_CommonRare function: joint test for common and rare variants
SKAT_ChrX function: X-chromosome test
SKAT_NULL_emmaX function: Kinship adjustment
SSD functions: plink binary file related functions
Power_Continuous, ...: power calculation functions
Add the following code to your website.
For more information on customizing the embed code, read Embedding Snippets.