Description Usage Arguments Value Note References
Calculate Bimodal Index
1 |
dataset |
A matrix or data.frame, usually with columns representing samples and rows representing genes or proteins. |
na.rm |
Logical. If remove na before calculating bi. If False, bi will not be calculated for any row with NA, |
verbose |
A logical value; should the function output a stream of information while it is working? |
Returns a data frame containing six columns, with the rows corresponding to the rows of the original data set. The columns contain the four parameters from the normal mixture model (mu1, mu2, sigma, and pi) along with the standardized distance delta and the bimodal index BI.
update from bimodalIndex BimodalIndex
Wang J, Wen S, Symmans WF, Pusztai L, Coombes KR. The bimodality index: A criterion for discovering and ranking bimodal signatures from cancer gene expression profiling data. Cancer Informatics, 2009 Aug 5; 7:199<e2><80><93>216.
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