| zimed | R Documentation |
The effect decomposition of mediation analysis for zero-inflated models in microbiome data
zimed(M_mat, Treat, Outcome, method, ci.method)
M_mat |
a data frame or matrix of the microbiome count data. Rows of the matrix represent samples and columns are the taxa |
Treat |
a binary vector of group indicators |
Outcome |
a continuous outcome |
method |
methods for testing the H0 hypothesis, including joint, HDMT or DACT |
ci.method |
methods for calculating confidence interval, including bootstrap or delta |
NIE the estimated natural indirect effect
NIE.p the calculated p value for NIE
NIE.ci the calculated confidence interval for NIE
NIEA the estimated natural indirect effect through changes of abundance
NIEA.p the calculated p value for NIEA
NIEA.ci the calculated confidence interval for NIEA
NIEP the estimated natural indirect effect through changes of absence/presence
NIEP.p the calculated p value for NIEP
NIEP.ci the calculated confidence interval for NIEP
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