Offers a gene-based meta-analysis test with filtering to detect gene-environment interactions (GxE) with association data. It first conducts a meta-filtering test to filter out unpromising SNPs by combining all samples in the consortia data. It then runs a test of omnibus-filtering-based GxE meta-analysis (ofGEM) that combines the strengths of the fixed- and random-effects meta-analysis with meta-filtering. It can also analyze data from multiple ethnic groups.
|Author||Jiebiao Wang, Qianying Liu and Lin S. Chen|
|Maintainer||Jiebiao Wang <[email protected]>|
|Package repository||View on GitHub|
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