lschen-stat/ofGEM: A Meta-Analysis Approach with Filtering for Identifying Gene-Level Gene-Environment Interactions with Genetic Association Data
Version 1.0

Offers a gene-based meta-analysis test with filtering to detect gene-environment interactions (GxE) with association data. It first conducts a meta-filtering test to filter out unpromising SNPs by combining all samples in the consortia data. It then runs a test of omnibus-filtering-based GxE meta-analysis (ofGEM) that combines the strengths of the fixed- and random-effects meta-analysis with meta-filtering. It can also analyze data from multiple ethnic groups.

Getting started

Package details

AuthorJiebiao Wang, Qianying Liu and Lin S. Chen
MaintainerJiebiao Wang <[email protected]>
LicenseGPL
Version1.0
URL https://github.com/randel/ofGEM
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
install.packages("devtools")
library(devtools)
install_github("lschen-stat/ofGEM")
lschen-stat/ofGEM documentation built on Aug. 9, 2017, 12:05 a.m.