lschen-stat/ofGEM: A Meta-Analysis Approach with Filtering for Identifying Gene-Level Gene-Environment Interactions with Genetic Association Data
Offers a gene-based meta-analysis test with filtering to detect gene-environment interactions (GxE) with association data. It first conducts a meta-filtering test to filter out unpromising SNPs by combining all samples in the consortia data. It then runs a test of omnibus-filtering-based GxE meta-analysis (ofGEM) that combines the strengths of the fixed- and random-effects meta-analysis with meta-filtering. It can also analyze data from multiple ethnic groups.
Getting started
Browse package contents
Package details |
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| Author | Jiebiao Wang, Qianying Liu and Lin S. Chen |
| Maintainer | Jiebiao Wang <randel.wang@gmail.com> |
| License | GPL |
| Version | 1.0 |
| URL | https://github.com/randel/ofGEM |
| Package repository | View on GitHub |
| Installation |
Install the latest version of this package by entering the following in R:
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