luannnguyen/CHORD: Classifier of Homologous Recombination Deficiency

CHORD is a random forest model that uses the relative counts of somatic mutation contexts to predict homologous recombination deficiency (HRD). The primary contexts used by CHORD are deletions with flanking microhomology and 1-100kb structural duplications. Additionally, 1-100kb structural duplications are used to distinguish BRCA1-type HRD from BRCA2-type HRD.

Getting started

Package details

AuthorLuan N. Nguyen
MaintainerLuan N. Nguyen <n.l.nguyen-2@umcutrecht.nl>
LicenseMIT
Version2.03
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
install.packages("remotes")
remotes::install_github("luannnguyen/CHORD")
luannnguyen/CHORD documentation built on Aug. 25, 2023, 10:04 a.m.