CellCycleEnrichScore: Calculate cell-cycle z-score

In lyc-1995/MySeuratWrappers: My extentions to Seurat package

Description

Another method to assign cell-cycle phase by computing z-score

Usage

CellCycleEnrichScore(
  object,
  assay = NULL,
  s.features = NULL,
  g2m.features = NULL,
  min.cells = 3,
  N = 100,
  seed = 42
)

Arguments

object	A Seurat object
assay	Which assay to use
s.features	A vector of features associated with S phase
g2m.features	A vector of features associated with G2M phase
min.cells	Include features detected in at least this many cells
N	Number of random background feature sets, default is 100
seed	Set a random seed

Value

A Seurat object with the following columns added to object meta data: s.score, g2m.score, and phase

References

Mayer, C., Hafemeister, C., Bandler, R. C., Machold, R., Batista Brito, R., Jaglin, X., … Satija, R. (2018). Developmental diversification of cortical inhibitory interneurons. Nature, 555(7697), 457–462. https://doi.org/10.1038/nature25999

lyc-1995/MySeuratWrappers documentation built on June 30, 2020, 11:48 a.m.