Identify the dysregulated edges for each sample
1 2 3 4 5 6 7 8 9 10 11 12 13 14 | #Identifying the dysregulated edges in both two conditions
Input.exp=GetExampleData(exampleData="Exp.input")
# view first rows of data
head(Input.exp)
#obtain the sample label
Cancer_s=GetExampleData(exampleData="Cancer_s")
Normal_s=GetExampleData(exampleData="Normal_s")
#obtain the protein interaction network
Network=GetExampleData(exampleData="network")
#identify the dysregulated edges
DysCN=EdgeticDys_CN(Input.exp,Network,thr=0.01)
Input.exp=Input.exp[,Cancer_s]
DysC=EdgeticDys_CN(Input.exp,Network,thr=0.01)
Dys.net=EdgeticDys_both(DysCN,DysC)
|
DysCN |
The dysregulated network in cancer vs normal |
DysC |
The dysregulated network for specific cancer sample |
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