completeMatrix | R Documentation |
This function performs an iterative matrix completion algorithm to predict drug response for pre-clinical data when there are missing ('NA') values.
completeMatrix(senMat, nPerms = 50)
senMat |
A matrix of drug sensitivity data with missing ('NA') values. rownames() are samples (e.g. cell lines), and colnames() are drugs. |
nPerms |
The number of iterations that the EM-algorithm (expectation maximization approach) run. The default is 50, as previous findings recommend 50 iterations (https://genomebiology.biomedcentral.com/articles/10.1186/s13059-016-1050-9) |
A matrix of drug sensitivity scores without missing values. rownames() are samples, and colnames are drugs.
try(completeMatrix(senMat, nPerms = 50))
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