OR_msigdb.mouse1: A wrapper of over-representation approach, MSigDB, mouse

View source: R/enrichment.R

OR_msigdb.mouse1R Documentation

A wrapper of over-representation approach, MSigDB, mouse

Description

Over-representation approach, MSigDB, mouse wrapper 1

Usage

OR_msigdb.mouse1(
  gene,
  excel_file,
  species = "Mus musculus",
  universe = NULL,
  pvalueCutoff = 1,
  pAdjustMethod = "BH",
  minGSSize = 5,
  maxGSSize = 10000,
  qvalueCutoff = 1
)

Arguments

gene

a vector of gene symbol.

species

an one-element character vector of species. Default to "Mus musculus".

universe

background genes. If missing, the all genes listed in the database (eg TERM2GENE table) will be used as background.

pvalueCutoff

adjusted pvalue cutoff on enrichment tests to report

pAdjustMethod

one of "holm", "hochberg", "hommel", "bonferroni", "BH", "BY", "fdr", "none"

minGSSize

minimal size of genes annotated for testing

maxGSSize

maximal size of genes annotated for testing

qvalueCutoff

qvalue cutoff on enrichment tests to report as significant. Tests must pass i) pvalueCutoff on unadjusted pvalues, ii) pvalueCutoff on adjusted pvalues and iii) qvalueCutoff on qvalues to be reported.

Value

A enrichResult instance

Author(s)

Mark J Chen


markgene/mutils documentation built on March 23, 2022, 1:14 p.m.