olsgasp: olsgasp: A package for imputation in genetic methylation...

olsgaspR Documentation

olsgasp: A package for imputation in genetic methylation studies

Description

We propose a a method to predict the missing methylation levels. This method catches correlation structures among the methylation levels across genome sites and across samples. The regression function linking the methylation level to the covariates is modeled through a linear combination of the covariates together with latent factors. We assume the covariates' and latent factors' effects to be Gaussian random processes (GP).

Author(s)

Melina Ribaud

References

Melina Ribaud, Aurélie Labbe and Karim Oualkacha. Imputation in genetic methylation studies: A linear model of coregionalization (LMC) with informative covariates. 2022. hal-00000000


melinaR/olsgasp documentation built on March 11, 2023, 12:10 a.m.