auc_partial: Calculate partial AUC

In metrumresearchgroup/PKPDmisc: Pharmacokinetic and Pharmacodynamic Data Management Functions

Calculate partial AUC

Description

Calculate partial AUC

Usage

auc_partial(idv, dv, range = c(0, Inf))

Arguments

idv	independent variable (such as time)
dv	dependent variable (such as concentration)
range	time range for pauc calculation

Details

default range is 0 to tmax is recommended to be used alongside dplyr for ease of calculation if an individual does not have any value within the specified range a warning will be issued and an NA value will be returned. This is important if some individuals dropped out early and do not have all observations other individuals have.

See Also

s_pauc

Examples

library(PKPDmisc)
library(dplyr, quiet = TRUE)
df <- capitalize_names(sd_oral_richpk) 
head(df)
df %>% group_by(ID) %>% 
summarize(pAUC0_10 = auc_partial(TIME, CONC, c(0,10)))

df %>% group_by(ID) %>% 
summarize(auc0_tlast = auc_partial(TIME, CONC)) 

metrumresearchgroup/PKPDmisc documentation built on Oct. 21, 2022, 9:41 a.m.