mfjoneill/gwrpvr: Genome-Wide Regression P-Value (Gwrpv)

Computes the sample probability value (p-value) for the estimated coefficient from a standard genome-wide univariate regression. It computes the exact finite-sample p-value under the assumption that the measured phenotype (the dependent variable in the regression) has a known Bernoulli-normal mixture distribution. Finite-sample genome-wide regression p-values (Gwrpv) with a non-normally distributed phenotype (Gregory Connor and Michael O'Neill, bioRxiv 204727 <doi:10.1101/204727>).

install.packages("remotes")
remotes::install_github("mfjoneill/gwrpvr")