plot.bcrm | R Documentation |
The estimated dose-toxicity curve using the Bayesian continuous reassessment method is plotted for the patients thus far recruited into the trial
## S3 method for class 'bcrm' plot(x, file = NULL, each = FALSE, trajectory = FALSE, ...)
x |
An object of class "bcrm", as returned by |
file |
File name where the dose-response plots are stored, in a pdf format. The program will amend the current sample size to the end of the file name. |
each |
Should posterior summaries be plotted after each recruited cohort? Defaults to FALSE. |
trajectory |
Should the sequential dose trajectory of the recruited patients be plotted, along with the observed toxicities? Defaults to FALSE. |
... |
Further arguments passed to or from other methods |
The estimated 2.5%, 25%, 50%, 75%, 97.5% quantiles of the probability of toxicity are plotted for each dose. Additionally, a histogram of the number of toxicities and non-toxicities is plotted at each experimented dose.
If trajectory = TRUE
then the sequential dose trajectory and observed
toxicities are plotted.
Michael Sweeting mjs212@medschl.cam.ac.uk (University of Cambridge, UK)
Sweeting M., Mander A., Sabin T. bcrm: Bayesian Continual Reassessment Method Designs for Phase I Dose-Finding Trials. Journal of Statistical Software (2013) 54: 1–26. doi: 10.18637/jss.v054.i13
bcrm
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