README.md

This repository contains the R package now hosted on Bioconductor and our current GitHub version.

Installation

(Mac Users Only:) Ensure you have installed XQuartz first.

Latest Bioconductor Release

Make sure you have the latest R version and the latest BiocManager package installed following these instructions (if you use legacy R versions (\<=3.5.0) refer to the instructions at the end of the mentioned page), you can then install mixOmics using the following code:

## install BiocManager if not installed
if (!requireNamespace("BiocManager", quietly = TRUE))
    install.packages("BiocManager")
## install mixOmics
BiocManager::install('mixOmics')

Latest GitHub Version

Install the devtools package in R, then load it and install the latest stable version of mixOmics from GitHub (as bug-free as it can be):

## install devtools if not installed
if (!requireNamespace("devtools", quietly = TRUE))
    install.packages("devtools")
## install mixOmics
devtools::install_github("mixOmicsTeam/mixOmics")

You can also install the development version:

devtools::install_github("mixOmicsTeam/mixOmics", ref="devel")

Check after installation that the following code does not throw any error (especially Mac users - refer to installation instructions) and that the welcome message confirms you have installed latest version as in the latest package DESCRIPTION file:

library(mixOmics) 
#> Loaded mixOmics ?.?.?

Community

Contributions

We welcome contributions that respect our code of conduct. We also strongly recommend adhering to Bioconductor’s coding guidelines when possible, for software consistency and smooth integration in our package. Thank you!

Bug reports and pull requests

To report a bug (or to offer a solution for a bug!): https://github.com/mixOmicsTeam/mixOmics/issues. We welcome well-formatted and detailed pull requests with examples run on our datasets.

Discussion forum

We wish to make our discussions transparent! Direct your questions to our discussion forum https://mixomics-users.discourse.group. This forum is aimed to host discussions on choices of multivariate analyses, bug report as well as comments and suggestions to improve the package. We hope to create an active community of users, data analysts, developers and R programmers alike! Thank you!

About the mixOmics team

mixOmics is collaborative project between Australia (Melbourne), France (Toulouse), and Canada (Vancouver). The core team includes Kim-Anh Lê Cao - https://lecao-lab.science.unimelb.edu.au (University of Melbourne), Florian Rohart - http://florian.rohart.free.fr (Toulouse) and Sébastien Déjean - https://perso.math.univ-toulouse.fr/dejean/. We also have key contributors, past (Benoît Gautier, François Bartolo) and present (Al Abadi, University of Melbourne) and several collaborators including Amrit Singh (University of British Columbia), Olivier Chapleur (IRSTEA, Paris), Antoine Bodein (Universite de Laval) - it could be you too, if you wish to be involved!.

The project started at the Institut de Mathématiques de Toulouse in France, and has been fully implemented in Australia, at the University of Queensland, Brisbane (2009 – 2016) and at the University of Melbourne, Australia (from 2017). We focus on the development of computational and statistical methods for biological data integration and their implementation in mixOmics.

Why this toolkit?

mixOmics offers a wide range of novel multivariate methods for the exploration and integration of biological datasets with a particular focus on variable selection. Single ‘omics analysis does not provide enough information to give a deep understanding of a biological system, but we can obtain a more holistic view of a system by combining multiple ‘omics analyses. Our mixOmics R package proposes a whole range of multivariate methods that we developed and validated on many biological studies to gain more insight into ‘omics biological studies.

Want to know more?

www.mixOmics.org (tutorials and resources)

Our latest bookdown vignette: https://mixomicsteam.github.io/Bookdown/.

Different types of methods

We have developed 17 novel multivariate methods (the package includes 19 methods in total). The names are full of acronyms, but are represented in this diagram. PLS stands for Projection to Latent Structures (also called Partial Least Squares, but not our prefered nomenclature), CCA for Canonical Correlation Analysis.

That’s it! Ready! Set! Go!

Thank you for using mixOmics!



mixOmicsTeam/mixOmics documentation built on Aug. 23, 2019, 1:32 p.m.