inst/shiny/multiarm/helpfiles/design_ratio_type.md

In mjg211/multiarm: Design of single- and multi-stage multi-arm clinical trials

Allocation ratios

multiarm requires values to be specified for the target (stage-wise amongst the remaining treatment arms, in the case of multi-stage designs) allocation ratios, r1, …, rK, of the number of patients to assign to experimental arms 1, …, K relative to the control arm. For a single-stage design, the options are that they are equal across all arms, equal across the experimental arms, unequal across all arms, based on the $\sqrt{K}$-rule ($r_1=\dots,r_K=1/\sqrt{K}$), or chosen for A-, D-, or E-optimality. For a multi-stage design, the options are that they are equal across all arms, equal across the experimental arms, or based on the $\sqrt{K}$-rule ($r_1=\dots,r_K=1/\sqrt{K}$). Specify your chosen type of allocation ratios here. Depending on your choice, suitable input boxes may then appear for you to specify the actual values of the allocation ratios.

mjg211/multiarm documentation built on Jan. 19, 2024, 8:21 a.m.