opchar_admissable: Determine the operating characteristics of admissable group...
In mjg211/singlearm: Design and analysis of single-arm clinical trials

Description Usage Arguments Details Value See Also Examples

opchar_admissable() supports the evaluation of the operating characteristics of admissable group sequential single-arm clinical trial designs for a single binary primary endpoint, determined using des_admissable().

1	opchar_admissable(des, k, pi, summary = F)

`des`	An object of class `"sa_des_admissable"`, as returned by `des_admissable()`.
`k`	Calculations are performed conditional on the trial stopping in one of the stages listed in vector `k`. Thus, `k` should be a vector of integers, with elements between one and the maximal number of possible stages in the supplied designs. If left unspecified, it will internally default to all possible stages.
`pi`	A vector of response probabilities to evaluate operating characteristics at. This will internally default to be the π₀ and π₁ from the supplied designs if it is left unspecified.
`summary`	A logical variable indicating whether a summary of the unction's progress should be printed to the console.

For each value of pi in the supplied vector pi, opchar_admissable() evaluates the power, ESS, and other key characteristics, of each of the supplied designs.

Calculations are performed conditional on the trial stopping in one of the stages specified using the input (vector) k.

A list of class "sa_opchar_admissable" containing the following elements

A tibble in the slot $opchar summarising the operating characteristics of the supplied designs.
Each of the input variables as specified, subject to internal modification.

des_admissable, and their associated plot family of functions.

# Find the admissable two-stage design for the default parameters
des         <- des_admissable()
# Determine operating characteristics for a range of response probabilities
opchar      <- opchar_admissable(des, pi = seq(0, 1, 0.01))