asl2p: Kinetic Models for Arterial Spin Labeling

In neuroconductor-devel/oro.asl: Rigorous - Aterial Spin Labelling

Kinetic Models for Arterial Spin Labeling

Description

Theoretical models for the acquisition of pulsed ASL data.

See Buxton etal. (1998) for more details.

Usage

asl2p(beta, TI, T1b = 1.3, T1 = 1, tau = 1, alpha = 0.9, lambda = 0.9,
  Mob = 4095)

asl3p(beta, TI, T1b = 1.3, T1 = 1, alpha = 0.9, lambda = 0.9,
  Mob = 100)

Arguments

beta	is a vector (lenth = 2 or 3) of kinetic parameters.
TI	is a vector of inversion times (TIs) in seconds.
T1b	is the longitudinal relaxation time of blood.
T1	is the longitudinal relaxation time of tissue.
tau	is the first TI in the second paper (?).
alpha	is the fraction of maximum possible change in the longitudinal magnetization that was achieved.
lambda	is the equilibrium tissue/blood partition coefficient of water.
Mob	is the equilibrium magnetization of arterial blood.

Value

A theoretical curve of pulsed ASL signal as a function of time.

Author(s)

Brandon Whitcher [e-mail]

References

Buxton, R.B., Frank, L.R., Wong, E.C., Siewert, B., Warach, S. and Edelman, R.R. (1998) A General Kinetic Model for Quantitative Perfusion Imaging with Arterial Spin Labeling, Magnetic Resonance in Medicine, 40, 383-396.

Examples

TI <- seq(0, 3, length=256)
beta <- c(f=0.8, deltaT=0.5)
plot(TI, asl2p(beta, TI), type="l", lwd=2,
     xlab="Time (sec)", ylab="Signal", main="Pulsed ASL: Standard Model")
abline(v=1.5, lwd=2, col=2)

neuroconductor-devel/oro.asl documentation built on July 3, 2025, 11:50 p.m.