rxAppendModel: Append two rxui models together

In nlmixr2/rxode2: Facilities for Simulating from ODE-Based Models

Append two rxui models together

Description

Append two rxui models together

Usage

rxAppendModel(..., common = TRUE)

Arguments

...	models to append together
common	boolean that determines if you need a common value to bind

Value

New model with both models appended together

Author(s)

Matthew L. Fidler

Examples

ocmt <- function() {
  ini({
    tka <- exp(0.45) # Ka
    tcl <- exp(1) # Cl
    tv <- exp(3.45); # log V
    ## the label("Label name") works with all models
    add.sd <- 0.7
  })
  model({
    ka <- tka
    cl <- tcl
    v <- tv
    d/dt(depot) <- -ka * depot
    d/dt(center) <- ka * depot - cl / v * center
    cp <- center / v
    cp ~ add(add.sd)
  })
}

idr <- function() {
  ini({
    tkin <- log(1)
    tkout <- log(1)
    tic50 <- log(10)
    gamma <- fix(1)
    idr.sd <- 1
  })
  model({
    kin <- exp(tkin)
    kout <- exp(tkout)
    ic50 <- exp(tic50)
    d/dt(eff) <- kin - kout*(1-ceff^gamma/(ic50^gamma+ceff^gamma))
    eff ~ add(idr.sd)
  })
}

rxAppendModel(ocmt %>% model(ceff=cp,append=TRUE), idr)

nlmixr2/rxode2 documentation built on Jan. 11, 2025, 8:48 a.m.