measure_separation: Measure separation of two entities (disease or drugs)

In nogay/drugdealR: Suggest Drug Combination Options for Comorbid Patients

Measure separation of two entities (disease or drugs)

Description

Measure separation of two entities (disease or drugs)

Usage

measure_separation(genesA, genesB, gr)

Arguments

genesA	list of genes associated with the given drug/disease.
genesB	list of genes associated with the given drug/disease.
gr	the subnetwork igraph graph object that contains all genes involved in diseases (according to DisNor) and drug targets (according to Drugbank) of interest.

Value

numeric

Examples

## Not run: 
library(drugdealR)
d <- load_interactome()

To calculate separation between two drugs, insert drug names
measure_separation(d$drug1_genes, d$drug2_genes, gr)

To calculate separation between two diseases, insert disease names
measure_separation(d$disease1_genes, d$disease2_genes, gr)

## End(Not run)

nogay/drugdealR documentation built on Sept. 25, 2022, 11:50 a.m.