The mmrm
package is based on previous work internal in Roche, namely
the tern
and tern.mmrm
packages which were based on lme4
.
The work done in the rbmi
package has been important since it used
glmmTMB
for fitting MMRMs.
We would like to thank Ben Bolker from the glmmTMB
team for multiple
discussions when we tried to get the Satterthwaite degrees of freedom
implemented with glmmTMB
(see https://github.com/glmmTMB/glmmTMB/blob/satterthwaite_df/glmmTMB/vignettes/satterthwaite_unstructured_example2.Rmd). Also Ben helped us significantly with
an example showing how to use TMB
for a random effect vector (https://github.com/bbolker/tmb-case-studies/tree/master/vectorMixed).
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