genePrioritization-package: genePrioritization - Find potential disease-related genes

Description Details Author(s)

Description

The genePrioritization package finds potential disease-related genes based on their coexpression with known disease-related "seed" genes, starting from a gene expression count matrix. The package computes a ranked co-expression list for each seed gene; each candidate gene is assigned the product of its ranks within these lists as a total score, according to which the candidates are finally ranked. Higher ranked genes should be functionally linked to the disease related genes and can thus have a role in the disease.

Details

Package: genePrioritization
Type: Package
Version: 0.99.4
Date: 2020-08-26
License: GPL-3

Author(s)

Chiara Paleni [aut, cre]
Politecnico di Milano
Maintainer: Chiara Paleni
E-Mail: <chiara.paleni@mail.polimi.it>


palenic/genePrioritization documentation built on Sept. 13, 2020, 12:16 a.m.