meffonym.quantile.normalization: Quantile normalization to a standard

View source: R/quantile-normalization.r

meffonym.quantile.normalizationR Documentation

Quantile normalization to a standard

Description

Methylation levels are quantile normalized so that they are comparable to a given dataset.

Usage

meffonym.quantile.normalization(x, standard, ...)

Arguments

x

DNA methylation matrix (rows=CpG sites, columns=samples).

standard

A named vector of methylation levels corresponding to the row names of x.

Value

Matrix identical to x but with methylation levels quantile normalized to the standard and rows corresponding to standard. Missing values in x are imputed by k-nearest neighbor.


perishky/meffonym documentation built on Nov. 8, 2024, 8:36 p.m.