calculate_individual_shrinkage: calculate_individual_shrinkage

In pharmpy/pharmr: Interface to the 'Pharmpy' 'Pharmacometrics' Library

calculate_individual_shrinkage

Description

Calculate the individual eta-shrinkage

Definition: ieta_shr = (var(eta) / omega)

Usage

calculate_individual_shrinkage(
  model,
  parameter_estimates,
  individual_estimates_covariance
)

Arguments

model	(Model) Pharmpy model
parameter_estimates	(array) Parameter estimates of model
individual_estimates_covariance	(data.frame) Uncertainty covariance matrices of individual estimates

Value

(DataFrame) Shrinkage for each eta and individual

See Also

calculate_eta_shrinkage

Examples

## Not run: 
model <- load_example_model("pheno")
results <- load_example_modelfit_results("pheno")
pe <- results$parameter_estimates
covs <- results$individual_estimates_covariance
calculate_individual_shrinkage(model, pe, covs)

## End(Not run)

pharmpy/pharmr documentation built on Feb. 15, 2025, 3:22 a.m.