simData: Simulate data according to the scDist model

In phillipnicol/pcDiffPop: Robust Identification of Perturbed Cell Types in Single-cell RNA-seq

Simulate data according to the scDist model

Description

Simulate data according to the scDist model

Usage

simData(nct = 10, J = 50, N1, N2, G = 1000, nn = 100, tau = 0.5)

Arguments

nct	The number of cell types.
J	The number of cells per cell type.
N1	The number of patients in first condition (reference).
N2	The number of patients in second condition.
G	The number of genes.
nn	The number of non-null genes between the conditions.
tau	The standard deviation of the patient-specific effect.

Value

A list with components

• Y - A matrix containing normalized counts (genes x cells).

• meta.data - Metadata that can be used as input to 'scDist'.

• D.true - The true distance

Author(s)

Phillip B. Nicol <[e-mail]>

phillipnicol/pcDiffPop documentation built on Nov. 29, 2024, 6:06 p.m.