Similar to the random forest correlation metric, but rather than Gini impurity indices we compute the coefficients corresponding to each gene with a LASSO regression model.
1 2 3 4 5 6 7 | lasso_coef_correlation(
expression_matrix,
pseudotime,
truetime,
milestones,
...
)
|
expression_matrix |
A p x n normalized gene expression matrix. |
pseudotime |
An n-vector of pseudotime estimates. |
truetime |
An n-vector of true timpoints. |
milestones |
A subset of the true time points, used to compute LASSO coefficients. |
... |
Additional parameters passed to |
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