twostg_power | R Documentation |
Determines the operating characteristics of single-arm, two-stage designs.
twostg_power(p0, pa, n1, n2, r1, r2) twostg_sim( p0, pa, n1, n2, r1 = seq.int(n1), r2 = seq.int(n1 + n2), plot = TRUE )
p0, pa |
probability of success under the null and alternative hypotheses, respectively |
n1, n2 |
sample size of first and second stage |
r1, r2 |
maximum number of responses in first stage and overall where treatment is declared ineffective |
plot |
logical; if |
twostg_power
returns vector with the following elements:
|
probability of stopping after the first stage
if |
|
probability of stopping after the first stage
if |
|
the overall type-I error |
|
the overall type-II error |
|
expected total sample size if |
|
expected total sample size if |
twostg_sim
returns a data frame with columns for each of the above
plus the following:
|
critical values for the first stage |
|
critical values for the second stage |
bin1samp_power
; bin1samp_sim
p0 <- 0.1 pa <- 0.3 des <- desmon2:::simon(p0, pa)$designs[1L, ] twostg_power(p0, pa, des[['n1']], des[['n2']], des[['r1']], des[['r2']]) ## compare des ## simulate over critical values twostg_sim(p0, pa, des[['n1']], des[['n2']]) ## Not run: res <- twostg_sim(p0, pa, des[['n1']], des[['n2']]) with(res, { iplotr::iscatter( type1, type2, group = type1 < 0.1 & type2 < 0.2, labels = list( r1 = r1, r2 = r2, alpha = round(type1, 3), power = round(1 - type2, 3) ) ) }) ## End(Not run)
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