A model of HIV infection with acute and chronic infection stages.
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deqn\fracdS(t)dt = \Lambda -\beta_1 c S(t) \fracI_1(t)N(t)-\beta_2 c S(t) \fracI_2(t)N(t)-\mu S(t)dS(t)/dt = -\Lambda -\beta_1 c S(t) I_1(t)/N(t)-\beta_2 c S(t) I_2(t)/N(t)-\mu S(t)
dI_1(t)/dt = β_1 c S(t) I_1(t)/N(t)+β_2 c S(t) I_2(t)/N(t) - (μ+α) I_1(t)
dI_2(t)/dt = α I_1(t)-(μ+γ)I_2(t)
The state variables of the model are as follows.
The number of susceptible individuals.
The number of individuals with acute HIV infection.
The number of individuals with chronic HIV infection.
Time is in weeks; years are assumed to comprise of 52 weeks. The parameters of the model, and the values used in the example, are as follows.
Symbol | Description | Value |
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