acutehiv: A model of HIV infection with acute and chronic infection...

Description Usage Details

Description

A model of HIV infection with acute and chronic infection stages.

Usage

1

Details

deqn\fracdS(t)dt = \Lambda -\beta_1 c S(t) \fracI_1(t)N(t)-\beta_2 c S(t) \fracI_2(t)N(t)-\mu S(t)dS(t)/dt = -\Lambda -\beta_1 c S(t) I_1(t)/N(t)-\beta_2 c S(t) I_2(t)/N(t)-\mu S(t)

dI_1(t)/dt = β_1 c S(t) I_1(t)/N(t)+β_2 c S(t) I_2(t)/N(t) - (μ+α) I_1(t)

dI_2(t)/dt = α I_1(t)-(μ+γ)I_2(t)

The state variables of the model are as follows.

S

The number of susceptible individuals.

I_1

The number of individuals with acute HIV infection.

I_2

The number of individuals with chronic HIV infection.

Time is in weeks; years are assumed to comprise of 52 weeks. The parameters of the model, and the values used in the example, are as follows.

Symbol Description Value

reconhub/epicookbook documentation built on May 27, 2019, 4:02 a.m.