find_drivers: ActiveDriverWGS analysis of cancer mutation information

Description Usage Arguments Value

Description

ActiveDriverWGS analysis of cancer mutation information

Usage

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find_drivers(prepared_elements, mutations_file, filter_hyper_MB = 30,
  mc.cores = 1, recovery_dir = NA)

Arguments

prepared_elements

the elements and active sites to analyze, as prepared by prepare_elements

mutations_file

path to a tab deliminated text file with 6 columns (chromosome, start position, end position, reference allele, alternate allele, patient identifier)

filter_hyper_MB

numeric specifying the mutation frequency to filter. Default value is 30

mc.cores

numeric indicating the number of computing cores to use. Default value is 1.

recovery_dir

path to a directory for ActiveDriverWGS to store intermediate computations in. In the case that find_drivers does not complete, run it again with the same value for this parameter, and it will read the intermediate computations rather than compute them again. Please specify a different directory, or delete the ActiveDriverWGS data in previously used directory, if running with different data. Default value is NA, and find_drivers will not save any intermediate information.

Value

data.frame containing all results from the ActiveDriverWGS analysis


reimandlab/ActiveDriverWGS documentation built on May 16, 2019, 7:47 a.m.