inst/About.md

Gerard Bouland, Joline Beulens, Joey Nap, Arno van der Slik, Arnaud Zaldumbide, Leen ’t Hart and Roderick Slieker    

CONQUER collects data from multiple resources. This page gives the overview of the used resources.    

Linkage disequilibrium (LD)

All SNPs in LD are retrieved from ENSEMBL REST API. The lead and LD (r2>0.8) SNPs are used in all subsequent analyses and lookups.    

QTL data

### eQTLs   Expression QTLs were obtained from GTEx. For all tested SNPs, CONQUER tests the lead SNP against all genes in cis and trans (those with an interaction) for all 44 tissues in GTEx. The precalculated eQTLs are used in the colocalization part.



roderickslieker/CONQUER documentation built on Nov. 12, 2021, 10:19 p.m.