LDscores: LD scores values

Description Usage Format References

Description

LD scores downloaded from <https://data.broadinstitute.org/alkesgroup/LDSCORE/1000G_Phase3_baseline_v1.1_ldscores.tgz> and compiled into a data.frame). LD scores are used in 'GetPleiotropyScore()'

Usage

1
data("LDscores")

Format

A data frame with 1,190,321 observations on the following 4 variables.

CHR

a numeric vector of chromosome number.

SNP

a character vector of RS ids (build 38).

BP

a numeric vector of chomosomal position.

baseL2

a numeric vector of LD scores.

References

Daniel Jordan*, Marie Verbanck* and Ron Do. HOPS: a quantitative score reveals pervasive horizontal pleiotropy in human genetic variation is driven by extreme polygenicity of human traits and diseases. Genome Biology 20, 222 (2019).


rondolab/PleiotropyScore documentation built on Aug. 4, 2020, 2:13 a.m.