Description Usage Format References
LD scores downloaded from <https://data.broadinstitute.org/alkesgroup/LDSCORE/1000G_Phase3_baseline_v1.1_ldscores.tgz> and compiled into a data.frame). LD scores are used in 'GetPleiotropyScore()'
1 | data("LDscores")
|
A data frame with 1,190,321 observations on the following 4 variables.
CHR
a numeric vector of chromosome number.
SNP
a character vector of RS ids (build 38).
BP
a numeric vector of chomosomal position.
baseL2
a numeric vector of LD scores.
Daniel Jordan*, Marie Verbanck* and Ron Do. HOPS: a quantitative score reveals pervasive horizontal pleiotropy in human genetic variation is driven by extreme polygenicity of human traits and diseases. Genome Biology 20, 222 (2019).
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