pk_oral_1cmt: Simulate PK data from a 1-compartment oral model

In ronkeizer/vpc: Create Visual Predictive Checks

Simulate PK data from a 1-compartment oral model

Description

Simulate PK data from a 1-compartment oral model

Usage

pk_oral_1cmt(t, tau = 24, dose = 120, ka = 1, ke = 1, cl = 10, ruv = NULL)

Arguments

t	Time after dose
tau	Dosing interval
dose	Dose
ka	Absorption rate
ke	Elimination rate
cl	Clearance
ruv	Residual variability

Value

A vector of predicted values, with or without added residual variability

Examples

dat1 <- vpc:::pk_oral_1cmt(t = c(0:72), tau = 24, dose = 120,
                     ka = 1, ke = 1, cl = 10)
dat2 <- vpc:::pk_oral_1cmt(t = c(0:72), tau = 24, dose = 120,
                     ka = 1, ke = 1, cl = 10,
                     ruv = list(proportional = 0.1, additive = 0.1))

ronkeizer/vpc documentation built on May 11, 2023, 11:09 p.m.