inst/QueryLibrary/Aggregate/condition_occurrence_combinations/COC01.md

In sib-swiss/dsQueryLibraryServer: OMOP query Library

COC01: Determines first line of therapy for a condition

Description

Query

The following is a sample run of the query. The input parameters are highlighted in blue

SELECT
  ingredient_name,
  ingredient_concept_id,
  count(*)::integer AS num_patients
FROM /*Drugs started by people up to 30 days after Angioedema diagnosis */ (
  SELECT
    condition.person_id,
    condition_start_date,
    drug_era_start_date,
    ingredient_name,
    ingredient_concept_id
  FROM /* people with Angioedema with 180 clean period and 180 day follow-up */ (
    SELECT
      era.person_id,
      condition_era_start_date AS condition_start_date
    FROM @cdm.condition_era era
    JOIN @cdm.observation_period obs
      ON obs.person_id = era.person_id AND
         era.condition_era_start_date >= obs.observation_period_start_date + 180*INTERVAL '1 day' AND
         era.condition_era_start_date <= obs.observation_period_end_date -180*INTERVAL '1 day'
    WHERE
      era.condition_concept_id IN 
      ( SELECT descendant_concept_id
        FROM @vocab.concept_ancestor
        WHERE ancestor_concept_id= $1)
  ) condition
  JOIN @cdm.drug_era rx /* Drug_era has drugs at ingredient level */
    ON rx.person_id = condition.person_id AND
       rx.drug_era_start_date >= condition.condition_start_date AND
       rx.drug_era_start_date <= condition.condition_start_date + 30*INTERVAL '1 day'
  JOIN /* Ingredients for indication Angioedema */ (
    SELECT
      ingredient.concept_id AS ingredient_concept_id ,
      ingredient.concept_name AS ingredient_name
    FROM @vocab.concept ingredient
    JOIN @vocab.concept_ancestor ca ON ca.descendant_concept_id = ingredient.concept_id
    WHERE
      ca.ancestor_concept_id = $2 /* indication for angioedema */ AND
      ingredient.concept_class_id ='Ingredient'
  ) ingredients ON ingredients.ingredient_concept_id = rx.drug_concept_id
) therapy
GROUP by ingredient_name, ingredient_concept_id
ORDER BY num_patients DESC;

Input

| Parameter | Example | Mandatory | Notes | | --- | --- | --- | --- | | condition_concept_id | 432791 | Yes | Angioedema | | ancestor_concept_id | 21003378 | Yes | Angioedema |

Output

| Field | Description | | --- | --- | | ingredient_name | | | ingredient_concept_id | | | count | |

Example output record

| Field | Description | | --- | --- | | ingredient_name | | | ingredient_concept_id | | | count | |

Documentation

https://github.com/OHDSI/CommonDataModel/wiki/

sib-swiss/dsQueryLibraryServer documentation built on Feb. 13, 2025, 8:07 p.m.