tests/testthat/_snaps/castle_integrated.md
In simondrue/castle: Fortify your ddPCR analyses for low-frequency variant detection
training model - snapshot
Code
train_integrated_ddpcr_model(background_samples = background_samples,
abc_grid_resolution = abc_grid_resolution)
Output
$a_est
[1] 5.125098e-07
$b_est
[1] 8.088402e-07
$c_est
[1] 0.1132381
$l_est_vec
[1] 0.3036824 0.5045560 0.6623755 0.0000000
$abc_grid
Var1 Var2 Var3
1 0.0000000001 0.0000000001 0.0000000001
2 0.0172699515 0.0000000001 0.0000000001
3 0.0345399029 0.0000000001 0.0000000001
4 0.0518098542 0.0000000001 0.0000000001
5 0.0690798056 0.0000000001 0.0000000001
6 0.0863497570 0.0000000001 0.0000000001
7 0.1036197084 0.0000000001 0.0000000001
8 0.0000000001 0.0316961235 0.0000000001
9 0.0172699515 0.0316961235 0.0000000001
10 0.0345399029 0.0316961235 0.0000000001
11 0.0518098542 0.0316961235 0.0000000001
12 0.0690798056 0.0316961235 0.0000000001
13 0.0863497570 0.0316961235 0.0000000001
14 0.1036197084 0.0316961235 0.0000000001
15 0.0000000001 0.0633922469 0.0000000001
16 0.0172699515 0.0633922469 0.0000000001
17 0.0345399029 0.0633922469 0.0000000001
18 0.0518098542 0.0633922469 0.0000000001
19 0.0690798056 0.0633922469 0.0000000001
20 0.0863497570 0.0633922469 0.0000000001
21 0.1036197084 0.0633922469 0.0000000001
22 0.0000000001 0.0950883704 0.0000000001
23 0.0172699515 0.0950883704 0.0000000001
24 0.0345399029 0.0950883704 0.0000000001
25 0.0518098542 0.0950883704 0.0000000001
26 0.0690798056 0.0950883704 0.0000000001
27 0.0863497570 0.0950883704 0.0000000001
28 0.1036197084 0.0950883704 0.0000000001
29 0.0000000001 0.1267844938 0.0000000001
30 0.0172699515 0.1267844938 0.0000000001
31 0.0345399029 0.1267844938 0.0000000001
32 0.0518098542 0.1267844938 0.0000000001
33 0.0690798056 0.1267844938 0.0000000001
34 0.0863497570 0.1267844938 0.0000000001
35 0.1036197084 0.1267844938 0.0000000001
36 0.0000000001 0.1584806172 0.0000000001
37 0.0172699515 0.1584806172 0.0000000001
38 0.0345399029 0.1584806172 0.0000000001
39 0.0518098542 0.1584806172 0.0000000001
40 0.0690798056 0.1584806172 0.0000000001
41 0.0863497570 0.1584806172 0.0000000001
42 0.1036197084 0.1584806172 0.0000000001
43 0.0000000001 0.1901767406 0.0000000001
44 0.0172699515 0.1901767406 0.0000000001
45 0.0345399029 0.1901767406 0.0000000001
46 0.0518098542 0.1901767406 0.0000000001
47 0.0690798056 0.1901767406 0.0000000001
48 0.0863497570 0.1901767406 0.0000000001
49 0.1036197084 0.1901767406 0.0000000001
50 0.0000000001 0.0000000001 0.0617040438
51 0.0172699515 0.0000000001 0.0617040438
52 0.0345399029 0.0000000001 0.0617040438
53 0.0518098542 0.0000000001 0.0617040438
54 0.0690798056 0.0000000001 0.0617040438
55 0.0863497570 0.0000000001 0.0617040438
56 0.1036197084 0.0000000001 0.0617040438
57 0.0000000001 0.0316961235 0.0617040438
58 0.0172699515 0.0316961235 0.0617040438
59 0.0345399029 0.0316961235 0.0617040438
60 0.0518098542 0.0316961235 0.0617040438
61 0.0690798056 0.0316961235 0.0617040438
62 0.0863497570 0.0316961235 0.0617040438
63 0.1036197084 0.0316961235 0.0617040438
64 0.0000000001 0.0633922469 0.0617040438
65 0.0172699515 0.0633922469 0.0617040438
66 0.0345399029 0.0633922469 0.0617040438
67 0.0518098542 0.0633922469 0.0617040438
68 0.0690798056 0.0633922469 0.0617040438
69 0.0863497570 0.0633922469 0.0617040438
70 0.1036197084 0.0633922469 0.0617040438
71 0.0000000001 0.0950883704 0.0617040438
72 0.0172699515 0.0950883704 0.0617040438
73 0.0345399029 0.0950883704 0.0617040438
74 0.0518098542 0.0950883704 0.0617040438
75 0.0690798056 0.0950883704 0.0617040438
76 0.0863497570 0.0950883704 0.0617040438
77 0.1036197084 0.0950883704 0.0617040438
78 0.0000000001 0.1267844938 0.0617040438
79 0.0172699515 0.1267844938 0.0617040438
80 0.0345399029 0.1267844938 0.0617040438
81 0.0518098542 0.1267844938 0.0617040438
82 0.0690798056 0.1267844938 0.0617040438
83 0.0863497570 0.1267844938 0.0617040438
84 0.1036197084 0.1267844938 0.0617040438
85 0.0000000001 0.1584806172 0.0617040438
86 0.0172699515 0.1584806172 0.0617040438
87 0.0345399029 0.1584806172 0.0617040438
88 0.0518098542 0.1584806172 0.0617040438
89 0.0690798056 0.1584806172 0.0617040438
90 0.0863497570 0.1584806172 0.0617040438
91 0.1036197084 0.1584806172 0.0617040438
92 0.0000000001 0.1901767406 0.0617040438
93 0.0172699515 0.1901767406 0.0617040438
94 0.0345399029 0.1901767406 0.0617040438
95 0.0518098542 0.1901767406 0.0617040438
96 0.0690798056 0.1901767406 0.0617040438
97 0.0863497570 0.1901767406 0.0617040438
98 0.1036197084 0.1901767406 0.0617040438
99 0.0000000001 0.0000000001 0.1234080876
100 0.0172699515 0.0000000001 0.1234080876
101 0.0345399029 0.0000000001 0.1234080876
102 0.0518098542 0.0000000001 0.1234080876
103 0.0690798056 0.0000000001 0.1234080876
104 0.0863497570 0.0000000001 0.1234080876
105 0.1036197084 0.0000000001 0.1234080876
106 0.0000000001 0.0316961235 0.1234080876
107 0.0172699515 0.0316961235 0.1234080876
108 0.0345399029 0.0316961235 0.1234080876
109 0.0518098542 0.0316961235 0.1234080876
110 0.0690798056 0.0316961235 0.1234080876
111 0.0863497570 0.0316961235 0.1234080876
112 0.1036197084 0.0316961235 0.1234080876
113 0.0000000001 0.0633922469 0.1234080876
114 0.0172699515 0.0633922469 0.1234080876
115 0.0345399029 0.0633922469 0.1234080876
116 0.0518098542 0.0633922469 0.1234080876
117 0.0690798056 0.0633922469 0.1234080876
118 0.0863497570 0.0633922469 0.1234080876
119 0.1036197084 0.0633922469 0.1234080876
120 0.0000000001 0.0950883704 0.1234080876
121 0.0172699515 0.0950883704 0.1234080876
122 0.0345399029 0.0950883704 0.1234080876
123 0.0518098542 0.0950883704 0.1234080876
124 0.0690798056 0.0950883704 0.1234080876
125 0.0863497570 0.0950883704 0.1234080876
126 0.1036197084 0.0950883704 0.1234080876
127 0.0000000001 0.1267844938 0.1234080876
128 0.0172699515 0.1267844938 0.1234080876
129 0.0345399029 0.1267844938 0.1234080876
130 0.0518098542 0.1267844938 0.1234080876
131 0.0690798056 0.1267844938 0.1234080876
132 0.0863497570 0.1267844938 0.1234080876
133 0.1036197084 0.1267844938 0.1234080876
134 0.0000000001 0.1584806172 0.1234080876
135 0.0172699515 0.1584806172 0.1234080876
136 0.0345399029 0.1584806172 0.1234080876
137 0.0518098542 0.1584806172 0.1234080876
138 0.0690798056 0.1584806172 0.1234080876
139 0.0863497570 0.1584806172 0.1234080876
140 0.1036197084 0.1584806172 0.1234080876
141 0.0000000001 0.1901767406 0.1234080876
142 0.0172699515 0.1901767406 0.1234080876
143 0.0345399029 0.1901767406 0.1234080876
144 0.0518098542 0.1901767406 0.1234080876
145 0.0690798056 0.1901767406 0.1234080876
146 0.0863497570 0.1901767406 0.1234080876
147 0.1036197084 0.1901767406 0.1234080876
148 0.0000000001 0.0000000001 0.1851121313
149 0.0172699515 0.0000000001 0.1851121313
150 0.0345399029 0.0000000001 0.1851121313
151 0.0518098542 0.0000000001 0.1851121313
152 0.0690798056 0.0000000001 0.1851121313
153 0.0863497570 0.0000000001 0.1851121313
154 0.1036197084 0.0000000001 0.1851121313
155 0.0000000001 0.0316961235 0.1851121313
156 0.0172699515 0.0316961235 0.1851121313
157 0.0345399029 0.0316961235 0.1851121313
158 0.0518098542 0.0316961235 0.1851121313
159 0.0690798056 0.0316961235 0.1851121313
160 0.0863497570 0.0316961235 0.1851121313
161 0.1036197084 0.0316961235 0.1851121313
162 0.0000000001 0.0633922469 0.1851121313
163 0.0172699515 0.0633922469 0.1851121313
164 0.0345399029 0.0633922469 0.1851121313
165 0.0518098542 0.0633922469 0.1851121313
166 0.0690798056 0.0633922469 0.1851121313
167 0.0863497570 0.0633922469 0.1851121313
168 0.1036197084 0.0633922469 0.1851121313
169 0.0000000001 0.0950883704 0.1851121313
170 0.0172699515 0.0950883704 0.1851121313
171 0.0345399029 0.0950883704 0.1851121313
172 0.0518098542 0.0950883704 0.1851121313
173 0.0690798056 0.0950883704 0.1851121313
174 0.0863497570 0.0950883704 0.1851121313
175 0.1036197084 0.0950883704 0.1851121313
176 0.0000000001 0.1267844938 0.1851121313
177 0.0172699515 0.1267844938 0.1851121313
178 0.0345399029 0.1267844938 0.1851121313
179 0.0518098542 0.1267844938 0.1851121313
180 0.0690798056 0.1267844938 0.1851121313
181 0.0863497570 0.1267844938 0.1851121313
182 0.1036197084 0.1267844938 0.1851121313
183 0.0000000001 0.1584806172 0.1851121313
184 0.0172699515 0.1584806172 0.1851121313
185 0.0345399029 0.1584806172 0.1851121313
186 0.0518098542 0.1584806172 0.1851121313
187 0.0690798056 0.1584806172 0.1851121313
188 0.0863497570 0.1584806172 0.1851121313
189 0.1036197084 0.1584806172 0.1851121313
190 0.0000000001 0.1901767406 0.1851121313
191 0.0172699515 0.1901767406 0.1851121313
192 0.0345399029 0.1901767406 0.1851121313
193 0.0518098542 0.1901767406 0.1851121313
194 0.0690798056 0.1901767406 0.1851121313
195 0.0863497570 0.1901767406 0.1851121313
196 0.1036197084 0.1901767406 0.1851121313
197 0.0000000001 0.0000000001 0.2468161751
198 0.0172699515 0.0000000001 0.2468161751
199 0.0345399029 0.0000000001 0.2468161751
200 0.0518098542 0.0000000001 0.2468161751
201 0.0690798056 0.0000000001 0.2468161751
202 0.0863497570 0.0000000001 0.2468161751
203 0.1036197084 0.0000000001 0.2468161751
204 0.0000000001 0.0316961235 0.2468161751
205 0.0172699515 0.0316961235 0.2468161751
206 0.0345399029 0.0316961235 0.2468161751
207 0.0518098542 0.0316961235 0.2468161751
208 0.0690798056 0.0316961235 0.2468161751
209 0.0863497570 0.0316961235 0.2468161751
210 0.1036197084 0.0316961235 0.2468161751
211 0.0000000001 0.0633922469 0.2468161751
212 0.0172699515 0.0633922469 0.2468161751
213 0.0345399029 0.0633922469 0.2468161751
214 0.0518098542 0.0633922469 0.2468161751
215 0.0690798056 0.0633922469 0.2468161751
216 0.0863497570 0.0633922469 0.2468161751
217 0.1036197084 0.0633922469 0.2468161751
218 0.0000000001 0.0950883704 0.2468161751
219 0.0172699515 0.0950883704 0.2468161751
220 0.0345399029 0.0950883704 0.2468161751
221 0.0518098542 0.0950883704 0.2468161751
222 0.0690798056 0.0950883704 0.2468161751
223 0.0863497570 0.0950883704 0.2468161751
224 0.1036197084 0.0950883704 0.2468161751
225 0.0000000001 0.1267844938 0.2468161751
226 0.0172699515 0.1267844938 0.2468161751
227 0.0345399029 0.1267844938 0.2468161751
228 0.0518098542 0.1267844938 0.2468161751
229 0.0690798056 0.1267844938 0.2468161751
230 0.0863497570 0.1267844938 0.2468161751
231 0.1036197084 0.1267844938 0.2468161751
232 0.0000000001 0.1584806172 0.2468161751
233 0.0172699515 0.1584806172 0.2468161751
234 0.0345399029 0.1584806172 0.2468161751
235 0.0518098542 0.1584806172 0.2468161751
236 0.0690798056 0.1584806172 0.2468161751
237 0.0863497570 0.1584806172 0.2468161751
238 0.1036197084 0.1584806172 0.2468161751
239 0.0000000001 0.1901767406 0.2468161751
240 0.0172699515 0.1901767406 0.2468161751
241 0.0345399029 0.1901767406 0.2468161751
242 0.0518098542 0.1901767406 0.2468161751
243 0.0690798056 0.1901767406 0.2468161751
244 0.0863497570 0.1901767406 0.2468161751
245 0.1036197084 0.1901767406 0.2468161751
246 0.0000000001 0.0000000001 0.3085202188
247 0.0172699515 0.0000000001 0.3085202188
248 0.0345399029 0.0000000001 0.3085202188
249 0.0518098542 0.0000000001 0.3085202188
250 0.0690798056 0.0000000001 0.3085202188
251 0.0863497570 0.0000000001 0.3085202188
252 0.1036197084 0.0000000001 0.3085202188
253 0.0000000001 0.0316961235 0.3085202188
254 0.0172699515 0.0316961235 0.3085202188
255 0.0345399029 0.0316961235 0.3085202188
256 0.0518098542 0.0316961235 0.3085202188
257 0.0690798056 0.0316961235 0.3085202188
258 0.0863497570 0.0316961235 0.3085202188
259 0.1036197084 0.0316961235 0.3085202188
260 0.0000000001 0.0633922469 0.3085202188
261 0.0172699515 0.0633922469 0.3085202188
262 0.0345399029 0.0633922469 0.3085202188
263 0.0518098542 0.0633922469 0.3085202188
264 0.0690798056 0.0633922469 0.3085202188
265 0.0863497570 0.0633922469 0.3085202188
266 0.1036197084 0.0633922469 0.3085202188
267 0.0000000001 0.0950883704 0.3085202188
268 0.0172699515 0.0950883704 0.3085202188
269 0.0345399029 0.0950883704 0.3085202188
270 0.0518098542 0.0950883704 0.3085202188
271 0.0690798056 0.0950883704 0.3085202188
272 0.0863497570 0.0950883704 0.3085202188
273 0.1036197084 0.0950883704 0.3085202188
274 0.0000000001 0.1267844938 0.3085202188
275 0.0172699515 0.1267844938 0.3085202188
276 0.0345399029 0.1267844938 0.3085202188
277 0.0518098542 0.1267844938 0.3085202188
278 0.0690798056 0.1267844938 0.3085202188
279 0.0863497570 0.1267844938 0.3085202188
280 0.1036197084 0.1267844938 0.3085202188
281 0.0000000001 0.1584806172 0.3085202188
282 0.0172699515 0.1584806172 0.3085202188
283 0.0345399029 0.1584806172 0.3085202188
284 0.0518098542 0.1584806172 0.3085202188
285 0.0690798056 0.1584806172 0.3085202188
286 0.0863497570 0.1584806172 0.3085202188
287 0.1036197084 0.1584806172 0.3085202188
288 0.0000000001 0.1901767406 0.3085202188
289 0.0172699515 0.1901767406 0.3085202188
290 0.0345399029 0.1901767406 0.3085202188
291 0.0518098542 0.1901767406 0.3085202188
292 0.0690798056 0.1901767406 0.3085202188
293 0.0863497570 0.1901767406 0.3085202188
294 0.1036197084 0.1901767406 0.3085202188
295 0.0000000001 0.0000000001 0.3702242625
296 0.0172699515 0.0000000001 0.3702242625
297 0.0345399029 0.0000000001 0.3702242625
298 0.0518098542 0.0000000001 0.3702242625
299 0.0690798056 0.0000000001 0.3702242625
300 0.0863497570 0.0000000001 0.3702242625
301 0.1036197084 0.0000000001 0.3702242625
302 0.0000000001 0.0316961235 0.3702242625
303 0.0172699515 0.0316961235 0.3702242625
304 0.0345399029 0.0316961235 0.3702242625
305 0.0518098542 0.0316961235 0.3702242625
306 0.0690798056 0.0316961235 0.3702242625
307 0.0863497570 0.0316961235 0.3702242625
308 0.1036197084 0.0316961235 0.3702242625
309 0.0000000001 0.0633922469 0.3702242625
310 0.0172699515 0.0633922469 0.3702242625
311 0.0345399029 0.0633922469 0.3702242625
312 0.0518098542 0.0633922469 0.3702242625
313 0.0690798056 0.0633922469 0.3702242625
314 0.0863497570 0.0633922469 0.3702242625
315 0.1036197084 0.0633922469 0.3702242625
316 0.0000000001 0.0950883704 0.3702242625
317 0.0172699515 0.0950883704 0.3702242625
318 0.0345399029 0.0950883704 0.3702242625
319 0.0518098542 0.0950883704 0.3702242625
320 0.0690798056 0.0950883704 0.3702242625
321 0.0863497570 0.0950883704 0.3702242625
322 0.1036197084 0.0950883704 0.3702242625
323 0.0000000001 0.1267844938 0.3702242625
324 0.0172699515 0.1267844938 0.3702242625
325 0.0345399029 0.1267844938 0.3702242625
326 0.0518098542 0.1267844938 0.3702242625
327 0.0690798056 0.1267844938 0.3702242625
328 0.0863497570 0.1267844938 0.3702242625
329 0.1036197084 0.1267844938 0.3702242625
330 0.0000000001 0.1584806172 0.3702242625
331 0.0172699515 0.1584806172 0.3702242625
332 0.0345399029 0.1584806172 0.3702242625
333 0.0518098542 0.1584806172 0.3702242625
334 0.0690798056 0.1584806172 0.3702242625
335 0.0863497570 0.1584806172 0.3702242625
336 0.1036197084 0.1584806172 0.3702242625
337 0.0000000001 0.1901767406 0.3702242625
338 0.0172699515 0.1901767406 0.3702242625
339 0.0345399029 0.1901767406 0.3702242625
340 0.0518098542 0.1901767406 0.3702242625
341 0.0690798056 0.1901767406 0.3702242625
342 0.0863497570 0.1901767406 0.3702242625
343 0.1036197084 0.1901767406 0.3702242625
$abc_grid_train_log_lik
[1] -305.6628 -143.7841 -140.7317 -140.2683 -140.8647 -142.0417 -143.5858
[8] -251.8046 -142.7153 -140.9504 -141.0774 -142.0193 -143.4244 -145.1309
[15] -252.2408 -143.6410 -142.1750 -142.5046 -143.5931 -145.1095 -146.9032
[22] -253.5206 -145.1034 -143.7715 -144.2039 -145.3736 -146.9559 -148.8042
[29] -255.1351 -146.8136 -145.5578 -146.0523 -147.2737 -148.8995 -150.7851
[36] -256.9252 -148.6625 -147.4559 -147.9919 -149.2490 -150.9058 -152.8185
[43] -258.8204 -150.5976 -149.4252 -149.9910 -151.2742 -152.9541 -154.8874
[50] -140.1261 -139.2719 -139.7182 -140.8167 -142.3130 -144.0782 -146.0380
[57] -140.0169 -139.9344 -140.7888 -142.1450 -143.8198 -145.7165 -147.7772
[64] -141.1599 -141.3081 -142.3249 -143.8019 -145.5703 -147.5418 -149.6637
[71] -142.7193 -142.9796 -144.0839 -145.6312 -147.4573 -149.4770 -151.6398
[78] -144.4844 -144.8110 -145.9700 -147.5632 -149.4284 -151.4818 -153.6739
[85] -146.3686 -146.7392 -147.9357 -149.5612 -151.4546 -153.5329 -155.7470
[92] -148.3283 -148.7300 -149.9537 -151.6033 -153.5180 -155.6153 -157.8466
[99] -138.7922 -139.7185 -141.1226 -142.8313 -144.7529 -146.8328 -149.0349
[106] -139.7123 -140.9592 -142.5722 -144.4293 -146.4623 -148.6291 -150.9010
[113] -141.1931 -142.5770 -144.2937 -146.2321 -148.3308 -150.5518 -152.8693
[120] -142.9236 -144.3841 -146.1629 -148.1528 -150.2950 -152.5530 -154.9025
[127] -144.7923 -146.3019 -148.1222 -150.1476 -152.3205 -154.6055 -156.9787
[134] -146.7462 -148.2899 -150.1399 -152.1913 -154.3872 -156.6925 -159.0841
[141] -148.7558 -150.3247 -152.1969 -154.2681 -156.4818 -158.8032 -161.2093
[148] -140.0465 -141.6595 -143.5214 -145.5606 -147.7334 -150.0111 -152.3734
[155] -141.4090 -143.2000 -145.1900 -147.3265 -149.5761 -151.9160 -154.3298
[162] -143.0909 -144.9732 -147.0356 -149.2309 -151.5295 -153.9107 -156.3598
[169] -144.9377 -146.8760 -148.9850 -151.2199 -153.5524 -155.9630 -158.4380
[176] -146.8826 -148.8588 -151.0004 -153.2637 -155.6211 -158.0538 -160.5485
[183] -148.8902 -150.8938 -153.0596 -155.3442 -157.7207 -160.1706 -162.6807
[190] -150.9398 -152.9642 -155.1485 -157.4498 -159.8414 -162.3049 -164.8276
[197] -142.3600 -144.3385 -146.4697 -148.7172 -151.0566 -153.4709 -155.9474
[204] -143.9716 -146.0638 -148.2819 -150.5984 -152.9941 -155.4553 -157.9714
[211] -145.7876 -147.9452 -150.2169 -152.5780 -155.0117 -157.5055 -160.0500
[218] -147.7190 -149.9194 -152.2275 -154.6200 -157.0810 -159.5988 -162.1646
[225] -149.7223 -151.9529 -154.2874 -156.7032 -159.1848 -161.7210 -164.3035
[232] -151.7728 -154.0259 -156.3804 -158.8141 -161.3119 -163.8627 -166.4585
[239] -153.8552 -156.1257 -158.4960 -160.9439 -163.4546 -166.0173 -168.6239
[246] -145.2535 -147.4591 -149.7679 -152.1590 -154.6172 -157.1316 -159.6938
[253] -147.0255 -149.3100 -151.6819 -154.1245 -156.6258 -159.1769 -161.7706
[260] -148.9374 -151.2712 -153.6843 -156.1621 -158.6938 -161.2713 -163.8883
[267] -150.9333 -153.3009 -155.7432 -158.2464 -160.8007 -163.3982 -166.0331
[274] -152.9829 -155.3752 -157.8393 -160.3620 -162.9336 -165.5468 -168.1959
[281] -155.0684 -157.4795 -159.9606 -162.4985 -165.0839 -167.7098 -170.3704
[288] -157.1781 -159.6042 -162.0987 -164.6489 -167.2457 -169.8818 -172.5520
[295] -148.5135 -150.8739 -153.3088 -155.8048 -158.3521 -160.9432 -163.5721
[302] -150.3975 -152.8160 -155.2986 -157.8347 -160.4161 -163.0367 -165.6913
[309] -152.3817 -154.8386 -157.3540 -159.9184 -162.5247 -165.1671 -167.8413
[316] -154.4282 -156.9125 -159.4519 -162.0375 -164.6627 -167.3221 -170.0115
[323] -156.5155 -159.0204 -161.5781 -164.1802 -166.8202 -169.4931 -172.1948
[330] -158.6301 -161.1510 -163.7232 -166.3385 -168.9905 -171.6744 -174.3862
[337] -160.7631 -163.2968 -165.8808 -168.5068 -171.1687 -173.8617 -176.5820
simulation - training - test
Code
multiple_test_res
Output
DoubleNegativeDroplets DoublePositiveDroplets WildtypeOnlyDroplets
1 7521 644 4889
2 8466 152 5252
MutantOnlyDroplets mutant_molecules_per_droplet
1 946 0.1006258337
2 130 0.0004839021
wildtype_molecules_per_droplet p_val test_statistic mutation_detected
1 0.5028811 0.0000000 3101.0031047 TRUE
2 0.4877604 0.6756611 0.1750512 FALSE
allele_frequency total_mutant_molecules total_wildtype_molecules
1 0.1667351811 1408.76167 7040.335
2 0.0009911067 6.77463 6828.645
mutant_molecules_per_droplet_CI_lower mutant_molecules_per_droplet_CI_upper
1 0.09300436 0.108582986
2 0.00000000 0.003658208
allele_frequency_CI_lower allele_frequency_CI_upper
1 0.1560776 0.177578689
2 0.0000000 0.007444179
total_mutant_molecules_CI_lower total_mutant_molecules_CI_upper
1 1302.061 1520.16181
2 0.000 51.21491
wildtype_molecules_per_droplet_CI_lower
1 0.4854383
2 0.4706541
wildtype_molecules_per_droplet_CI_upper
1 0.5207539
2 0.5052932
simondrue/castle documentation built on Jan. 29, 2022, 3:04 a.m.
R Package Documentation
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training model - snapshot
Code
train_integrated_ddpcr_model(background_samples = background_samples,
abc_grid_resolution = abc_grid_resolution)
Output
$a_est
[1] 5.125098e-07
$b_est
[1] 8.088402e-07
$c_est
[1] 0.1132381
$l_est_vec
[1] 0.3036824 0.5045560 0.6623755 0.0000000
$abc_grid
Var1 Var2 Var3
1 0.0000000001 0.0000000001 0.0000000001
2 0.0172699515 0.0000000001 0.0000000001
3 0.0345399029 0.0000000001 0.0000000001
4 0.0518098542 0.0000000001 0.0000000001
5 0.0690798056 0.0000000001 0.0000000001
6 0.0863497570 0.0000000001 0.0000000001
7 0.1036197084 0.0000000001 0.0000000001
8 0.0000000001 0.0316961235 0.0000000001
9 0.0172699515 0.0316961235 0.0000000001
10 0.0345399029 0.0316961235 0.0000000001
11 0.0518098542 0.0316961235 0.0000000001
12 0.0690798056 0.0316961235 0.0000000001
13 0.0863497570 0.0316961235 0.0000000001
14 0.1036197084 0.0316961235 0.0000000001
15 0.0000000001 0.0633922469 0.0000000001
16 0.0172699515 0.0633922469 0.0000000001
17 0.0345399029 0.0633922469 0.0000000001
18 0.0518098542 0.0633922469 0.0000000001
19 0.0690798056 0.0633922469 0.0000000001
20 0.0863497570 0.0633922469 0.0000000001
21 0.1036197084 0.0633922469 0.0000000001
22 0.0000000001 0.0950883704 0.0000000001
23 0.0172699515 0.0950883704 0.0000000001
24 0.0345399029 0.0950883704 0.0000000001
25 0.0518098542 0.0950883704 0.0000000001
26 0.0690798056 0.0950883704 0.0000000001
27 0.0863497570 0.0950883704 0.0000000001
28 0.1036197084 0.0950883704 0.0000000001
29 0.0000000001 0.1267844938 0.0000000001
30 0.0172699515 0.1267844938 0.0000000001
31 0.0345399029 0.1267844938 0.0000000001
32 0.0518098542 0.1267844938 0.0000000001
33 0.0690798056 0.1267844938 0.0000000001
34 0.0863497570 0.1267844938 0.0000000001
35 0.1036197084 0.1267844938 0.0000000001
36 0.0000000001 0.1584806172 0.0000000001
37 0.0172699515 0.1584806172 0.0000000001
38 0.0345399029 0.1584806172 0.0000000001
39 0.0518098542 0.1584806172 0.0000000001
40 0.0690798056 0.1584806172 0.0000000001
41 0.0863497570 0.1584806172 0.0000000001
42 0.1036197084 0.1584806172 0.0000000001
43 0.0000000001 0.1901767406 0.0000000001
44 0.0172699515 0.1901767406 0.0000000001
45 0.0345399029 0.1901767406 0.0000000001
46 0.0518098542 0.1901767406 0.0000000001
47 0.0690798056 0.1901767406 0.0000000001
48 0.0863497570 0.1901767406 0.0000000001
49 0.1036197084 0.1901767406 0.0000000001
50 0.0000000001 0.0000000001 0.0617040438
51 0.0172699515 0.0000000001 0.0617040438
52 0.0345399029 0.0000000001 0.0617040438
53 0.0518098542 0.0000000001 0.0617040438
54 0.0690798056 0.0000000001 0.0617040438
55 0.0863497570 0.0000000001 0.0617040438
56 0.1036197084 0.0000000001 0.0617040438
57 0.0000000001 0.0316961235 0.0617040438
58 0.0172699515 0.0316961235 0.0617040438
59 0.0345399029 0.0316961235 0.0617040438
60 0.0518098542 0.0316961235 0.0617040438
61 0.0690798056 0.0316961235 0.0617040438
62 0.0863497570 0.0316961235 0.0617040438
63 0.1036197084 0.0316961235 0.0617040438
64 0.0000000001 0.0633922469 0.0617040438
65 0.0172699515 0.0633922469 0.0617040438
66 0.0345399029 0.0633922469 0.0617040438
67 0.0518098542 0.0633922469 0.0617040438
68 0.0690798056 0.0633922469 0.0617040438
69 0.0863497570 0.0633922469 0.0617040438
70 0.1036197084 0.0633922469 0.0617040438
71 0.0000000001 0.0950883704 0.0617040438
72 0.0172699515 0.0950883704 0.0617040438
73 0.0345399029 0.0950883704 0.0617040438
74 0.0518098542 0.0950883704 0.0617040438
75 0.0690798056 0.0950883704 0.0617040438
76 0.0863497570 0.0950883704 0.0617040438
77 0.1036197084 0.0950883704 0.0617040438
78 0.0000000001 0.1267844938 0.0617040438
79 0.0172699515 0.1267844938 0.0617040438
80 0.0345399029 0.1267844938 0.0617040438
81 0.0518098542 0.1267844938 0.0617040438
82 0.0690798056 0.1267844938 0.0617040438
83 0.0863497570 0.1267844938 0.0617040438
84 0.1036197084 0.1267844938 0.0617040438
85 0.0000000001 0.1584806172 0.0617040438
86 0.0172699515 0.1584806172 0.0617040438
87 0.0345399029 0.1584806172 0.0617040438
88 0.0518098542 0.1584806172 0.0617040438
89 0.0690798056 0.1584806172 0.0617040438
90 0.0863497570 0.1584806172 0.0617040438
91 0.1036197084 0.1584806172 0.0617040438
92 0.0000000001 0.1901767406 0.0617040438
93 0.0172699515 0.1901767406 0.0617040438
94 0.0345399029 0.1901767406 0.0617040438
95 0.0518098542 0.1901767406 0.0617040438
96 0.0690798056 0.1901767406 0.0617040438
97 0.0863497570 0.1901767406 0.0617040438
98 0.1036197084 0.1901767406 0.0617040438
99 0.0000000001 0.0000000001 0.1234080876
100 0.0172699515 0.0000000001 0.1234080876
101 0.0345399029 0.0000000001 0.1234080876
102 0.0518098542 0.0000000001 0.1234080876
103 0.0690798056 0.0000000001 0.1234080876
104 0.0863497570 0.0000000001 0.1234080876
105 0.1036197084 0.0000000001 0.1234080876
106 0.0000000001 0.0316961235 0.1234080876
107 0.0172699515 0.0316961235 0.1234080876
108 0.0345399029 0.0316961235 0.1234080876
109 0.0518098542 0.0316961235 0.1234080876
110 0.0690798056 0.0316961235 0.1234080876
111 0.0863497570 0.0316961235 0.1234080876
112 0.1036197084 0.0316961235 0.1234080876
113 0.0000000001 0.0633922469 0.1234080876
114 0.0172699515 0.0633922469 0.1234080876
115 0.0345399029 0.0633922469 0.1234080876
116 0.0518098542 0.0633922469 0.1234080876
117 0.0690798056 0.0633922469 0.1234080876
118 0.0863497570 0.0633922469 0.1234080876
119 0.1036197084 0.0633922469 0.1234080876
120 0.0000000001 0.0950883704 0.1234080876
121 0.0172699515 0.0950883704 0.1234080876
122 0.0345399029 0.0950883704 0.1234080876
123 0.0518098542 0.0950883704 0.1234080876
124 0.0690798056 0.0950883704 0.1234080876
125 0.0863497570 0.0950883704 0.1234080876
126 0.1036197084 0.0950883704 0.1234080876
127 0.0000000001 0.1267844938 0.1234080876
128 0.0172699515 0.1267844938 0.1234080876
129 0.0345399029 0.1267844938 0.1234080876
130 0.0518098542 0.1267844938 0.1234080876
131 0.0690798056 0.1267844938 0.1234080876
132 0.0863497570 0.1267844938 0.1234080876
133 0.1036197084 0.1267844938 0.1234080876
134 0.0000000001 0.1584806172 0.1234080876
135 0.0172699515 0.1584806172 0.1234080876
136 0.0345399029 0.1584806172 0.1234080876
137 0.0518098542 0.1584806172 0.1234080876
138 0.0690798056 0.1584806172 0.1234080876
139 0.0863497570 0.1584806172 0.1234080876
140 0.1036197084 0.1584806172 0.1234080876
141 0.0000000001 0.1901767406 0.1234080876
142 0.0172699515 0.1901767406 0.1234080876
143 0.0345399029 0.1901767406 0.1234080876
144 0.0518098542 0.1901767406 0.1234080876
145 0.0690798056 0.1901767406 0.1234080876
146 0.0863497570 0.1901767406 0.1234080876
147 0.1036197084 0.1901767406 0.1234080876
148 0.0000000001 0.0000000001 0.1851121313
149 0.0172699515 0.0000000001 0.1851121313
150 0.0345399029 0.0000000001 0.1851121313
151 0.0518098542 0.0000000001 0.1851121313
152 0.0690798056 0.0000000001 0.1851121313
153 0.0863497570 0.0000000001 0.1851121313
154 0.1036197084 0.0000000001 0.1851121313
155 0.0000000001 0.0316961235 0.1851121313
156 0.0172699515 0.0316961235 0.1851121313
157 0.0345399029 0.0316961235 0.1851121313
158 0.0518098542 0.0316961235 0.1851121313
159 0.0690798056 0.0316961235 0.1851121313
160 0.0863497570 0.0316961235 0.1851121313
161 0.1036197084 0.0316961235 0.1851121313
162 0.0000000001 0.0633922469 0.1851121313
163 0.0172699515 0.0633922469 0.1851121313
164 0.0345399029 0.0633922469 0.1851121313
165 0.0518098542 0.0633922469 0.1851121313
166 0.0690798056 0.0633922469 0.1851121313
167 0.0863497570 0.0633922469 0.1851121313
168 0.1036197084 0.0633922469 0.1851121313
169 0.0000000001 0.0950883704 0.1851121313
170 0.0172699515 0.0950883704 0.1851121313
171 0.0345399029 0.0950883704 0.1851121313
172 0.0518098542 0.0950883704 0.1851121313
173 0.0690798056 0.0950883704 0.1851121313
174 0.0863497570 0.0950883704 0.1851121313
175 0.1036197084 0.0950883704 0.1851121313
176 0.0000000001 0.1267844938 0.1851121313
177 0.0172699515 0.1267844938 0.1851121313
178 0.0345399029 0.1267844938 0.1851121313
179 0.0518098542 0.1267844938 0.1851121313
180 0.0690798056 0.1267844938 0.1851121313
181 0.0863497570 0.1267844938 0.1851121313
182 0.1036197084 0.1267844938 0.1851121313
183 0.0000000001 0.1584806172 0.1851121313
184 0.0172699515 0.1584806172 0.1851121313
185 0.0345399029 0.1584806172 0.1851121313
186 0.0518098542 0.1584806172 0.1851121313
187 0.0690798056 0.1584806172 0.1851121313
188 0.0863497570 0.1584806172 0.1851121313
189 0.1036197084 0.1584806172 0.1851121313
190 0.0000000001 0.1901767406 0.1851121313
191 0.0172699515 0.1901767406 0.1851121313
192 0.0345399029 0.1901767406 0.1851121313
193 0.0518098542 0.1901767406 0.1851121313
194 0.0690798056 0.1901767406 0.1851121313
195 0.0863497570 0.1901767406 0.1851121313
196 0.1036197084 0.1901767406 0.1851121313
197 0.0000000001 0.0000000001 0.2468161751
198 0.0172699515 0.0000000001 0.2468161751
199 0.0345399029 0.0000000001 0.2468161751
200 0.0518098542 0.0000000001 0.2468161751
201 0.0690798056 0.0000000001 0.2468161751
202 0.0863497570 0.0000000001 0.2468161751
203 0.1036197084 0.0000000001 0.2468161751
204 0.0000000001 0.0316961235 0.2468161751
205 0.0172699515 0.0316961235 0.2468161751
206 0.0345399029 0.0316961235 0.2468161751
207 0.0518098542 0.0316961235 0.2468161751
208 0.0690798056 0.0316961235 0.2468161751
209 0.0863497570 0.0316961235 0.2468161751
210 0.1036197084 0.0316961235 0.2468161751
211 0.0000000001 0.0633922469 0.2468161751
212 0.0172699515 0.0633922469 0.2468161751
213 0.0345399029 0.0633922469 0.2468161751
214 0.0518098542 0.0633922469 0.2468161751
215 0.0690798056 0.0633922469 0.2468161751
216 0.0863497570 0.0633922469 0.2468161751
217 0.1036197084 0.0633922469 0.2468161751
218 0.0000000001 0.0950883704 0.2468161751
219 0.0172699515 0.0950883704 0.2468161751
220 0.0345399029 0.0950883704 0.2468161751
221 0.0518098542 0.0950883704 0.2468161751
222 0.0690798056 0.0950883704 0.2468161751
223 0.0863497570 0.0950883704 0.2468161751
224 0.1036197084 0.0950883704 0.2468161751
225 0.0000000001 0.1267844938 0.2468161751
226 0.0172699515 0.1267844938 0.2468161751
227 0.0345399029 0.1267844938 0.2468161751
228 0.0518098542 0.1267844938 0.2468161751
229 0.0690798056 0.1267844938 0.2468161751
230 0.0863497570 0.1267844938 0.2468161751
231 0.1036197084 0.1267844938 0.2468161751
232 0.0000000001 0.1584806172 0.2468161751
233 0.0172699515 0.1584806172 0.2468161751
234 0.0345399029 0.1584806172 0.2468161751
235 0.0518098542 0.1584806172 0.2468161751
236 0.0690798056 0.1584806172 0.2468161751
237 0.0863497570 0.1584806172 0.2468161751
238 0.1036197084 0.1584806172 0.2468161751
239 0.0000000001 0.1901767406 0.2468161751
240 0.0172699515 0.1901767406 0.2468161751
241 0.0345399029 0.1901767406 0.2468161751
242 0.0518098542 0.1901767406 0.2468161751
243 0.0690798056 0.1901767406 0.2468161751
244 0.0863497570 0.1901767406 0.2468161751
245 0.1036197084 0.1901767406 0.2468161751
246 0.0000000001 0.0000000001 0.3085202188
247 0.0172699515 0.0000000001 0.3085202188
248 0.0345399029 0.0000000001 0.3085202188
249 0.0518098542 0.0000000001 0.3085202188
250 0.0690798056 0.0000000001 0.3085202188
251 0.0863497570 0.0000000001 0.3085202188
252 0.1036197084 0.0000000001 0.3085202188
253 0.0000000001 0.0316961235 0.3085202188
254 0.0172699515 0.0316961235 0.3085202188
255 0.0345399029 0.0316961235 0.3085202188
256 0.0518098542 0.0316961235 0.3085202188
257 0.0690798056 0.0316961235 0.3085202188
258 0.0863497570 0.0316961235 0.3085202188
259 0.1036197084 0.0316961235 0.3085202188
260 0.0000000001 0.0633922469 0.3085202188
261 0.0172699515 0.0633922469 0.3085202188
262 0.0345399029 0.0633922469 0.3085202188
263 0.0518098542 0.0633922469 0.3085202188
264 0.0690798056 0.0633922469 0.3085202188
265 0.0863497570 0.0633922469 0.3085202188
266 0.1036197084 0.0633922469 0.3085202188
267 0.0000000001 0.0950883704 0.3085202188
268 0.0172699515 0.0950883704 0.3085202188
269 0.0345399029 0.0950883704 0.3085202188
270 0.0518098542 0.0950883704 0.3085202188
271 0.0690798056 0.0950883704 0.3085202188
272 0.0863497570 0.0950883704 0.3085202188
273 0.1036197084 0.0950883704 0.3085202188
274 0.0000000001 0.1267844938 0.3085202188
275 0.0172699515 0.1267844938 0.3085202188
276 0.0345399029 0.1267844938 0.3085202188
277 0.0518098542 0.1267844938 0.3085202188
278 0.0690798056 0.1267844938 0.3085202188
279 0.0863497570 0.1267844938 0.3085202188
280 0.1036197084 0.1267844938 0.3085202188
281 0.0000000001 0.1584806172 0.3085202188
282 0.0172699515 0.1584806172 0.3085202188
283 0.0345399029 0.1584806172 0.3085202188
284 0.0518098542 0.1584806172 0.3085202188
285 0.0690798056 0.1584806172 0.3085202188
286 0.0863497570 0.1584806172 0.3085202188
287 0.1036197084 0.1584806172 0.3085202188
288 0.0000000001 0.1901767406 0.3085202188
289 0.0172699515 0.1901767406 0.3085202188
290 0.0345399029 0.1901767406 0.3085202188
291 0.0518098542 0.1901767406 0.3085202188
292 0.0690798056 0.1901767406 0.3085202188
293 0.0863497570 0.1901767406 0.3085202188
294 0.1036197084 0.1901767406 0.3085202188
295 0.0000000001 0.0000000001 0.3702242625
296 0.0172699515 0.0000000001 0.3702242625
297 0.0345399029 0.0000000001 0.3702242625
298 0.0518098542 0.0000000001 0.3702242625
299 0.0690798056 0.0000000001 0.3702242625
300 0.0863497570 0.0000000001 0.3702242625
301 0.1036197084 0.0000000001 0.3702242625
302 0.0000000001 0.0316961235 0.3702242625
303 0.0172699515 0.0316961235 0.3702242625
304 0.0345399029 0.0316961235 0.3702242625
305 0.0518098542 0.0316961235 0.3702242625
306 0.0690798056 0.0316961235 0.3702242625
307 0.0863497570 0.0316961235 0.3702242625
308 0.1036197084 0.0316961235 0.3702242625
309 0.0000000001 0.0633922469 0.3702242625
310 0.0172699515 0.0633922469 0.3702242625
311 0.0345399029 0.0633922469 0.3702242625
312 0.0518098542 0.0633922469 0.3702242625
313 0.0690798056 0.0633922469 0.3702242625
314 0.0863497570 0.0633922469 0.3702242625
315 0.1036197084 0.0633922469 0.3702242625
316 0.0000000001 0.0950883704 0.3702242625
317 0.0172699515 0.0950883704 0.3702242625
318 0.0345399029 0.0950883704 0.3702242625
319 0.0518098542 0.0950883704 0.3702242625
320 0.0690798056 0.0950883704 0.3702242625
321 0.0863497570 0.0950883704 0.3702242625
322 0.1036197084 0.0950883704 0.3702242625
323 0.0000000001 0.1267844938 0.3702242625
324 0.0172699515 0.1267844938 0.3702242625
325 0.0345399029 0.1267844938 0.3702242625
326 0.0518098542 0.1267844938 0.3702242625
327 0.0690798056 0.1267844938 0.3702242625
328 0.0863497570 0.1267844938 0.3702242625
329 0.1036197084 0.1267844938 0.3702242625
330 0.0000000001 0.1584806172 0.3702242625
331 0.0172699515 0.1584806172 0.3702242625
332 0.0345399029 0.1584806172 0.3702242625
333 0.0518098542 0.1584806172 0.3702242625
334 0.0690798056 0.1584806172 0.3702242625
335 0.0863497570 0.1584806172 0.3702242625
336 0.1036197084 0.1584806172 0.3702242625
337 0.0000000001 0.1901767406 0.3702242625
338 0.0172699515 0.1901767406 0.3702242625
339 0.0345399029 0.1901767406 0.3702242625
340 0.0518098542 0.1901767406 0.3702242625
341 0.0690798056 0.1901767406 0.3702242625
342 0.0863497570 0.1901767406 0.3702242625
343 0.1036197084 0.1901767406 0.3702242625
$abc_grid_train_log_lik
[1] -305.6628 -143.7841 -140.7317 -140.2683 -140.8647 -142.0417 -143.5858
[8] -251.8046 -142.7153 -140.9504 -141.0774 -142.0193 -143.4244 -145.1309
[15] -252.2408 -143.6410 -142.1750 -142.5046 -143.5931 -145.1095 -146.9032
[22] -253.5206 -145.1034 -143.7715 -144.2039 -145.3736 -146.9559 -148.8042
[29] -255.1351 -146.8136 -145.5578 -146.0523 -147.2737 -148.8995 -150.7851
[36] -256.9252 -148.6625 -147.4559 -147.9919 -149.2490 -150.9058 -152.8185
[43] -258.8204 -150.5976 -149.4252 -149.9910 -151.2742 -152.9541 -154.8874
[50] -140.1261 -139.2719 -139.7182 -140.8167 -142.3130 -144.0782 -146.0380
[57] -140.0169 -139.9344 -140.7888 -142.1450 -143.8198 -145.7165 -147.7772
[64] -141.1599 -141.3081 -142.3249 -143.8019 -145.5703 -147.5418 -149.6637
[71] -142.7193 -142.9796 -144.0839 -145.6312 -147.4573 -149.4770 -151.6398
[78] -144.4844 -144.8110 -145.9700 -147.5632 -149.4284 -151.4818 -153.6739
[85] -146.3686 -146.7392 -147.9357 -149.5612 -151.4546 -153.5329 -155.7470
[92] -148.3283 -148.7300 -149.9537 -151.6033 -153.5180 -155.6153 -157.8466
[99] -138.7922 -139.7185 -141.1226 -142.8313 -144.7529 -146.8328 -149.0349
[106] -139.7123 -140.9592 -142.5722 -144.4293 -146.4623 -148.6291 -150.9010
[113] -141.1931 -142.5770 -144.2937 -146.2321 -148.3308 -150.5518 -152.8693
[120] -142.9236 -144.3841 -146.1629 -148.1528 -150.2950 -152.5530 -154.9025
[127] -144.7923 -146.3019 -148.1222 -150.1476 -152.3205 -154.6055 -156.9787
[134] -146.7462 -148.2899 -150.1399 -152.1913 -154.3872 -156.6925 -159.0841
[141] -148.7558 -150.3247 -152.1969 -154.2681 -156.4818 -158.8032 -161.2093
[148] -140.0465 -141.6595 -143.5214 -145.5606 -147.7334 -150.0111 -152.3734
[155] -141.4090 -143.2000 -145.1900 -147.3265 -149.5761 -151.9160 -154.3298
[162] -143.0909 -144.9732 -147.0356 -149.2309 -151.5295 -153.9107 -156.3598
[169] -144.9377 -146.8760 -148.9850 -151.2199 -153.5524 -155.9630 -158.4380
[176] -146.8826 -148.8588 -151.0004 -153.2637 -155.6211 -158.0538 -160.5485
[183] -148.8902 -150.8938 -153.0596 -155.3442 -157.7207 -160.1706 -162.6807
[190] -150.9398 -152.9642 -155.1485 -157.4498 -159.8414 -162.3049 -164.8276
[197] -142.3600 -144.3385 -146.4697 -148.7172 -151.0566 -153.4709 -155.9474
[204] -143.9716 -146.0638 -148.2819 -150.5984 -152.9941 -155.4553 -157.9714
[211] -145.7876 -147.9452 -150.2169 -152.5780 -155.0117 -157.5055 -160.0500
[218] -147.7190 -149.9194 -152.2275 -154.6200 -157.0810 -159.5988 -162.1646
[225] -149.7223 -151.9529 -154.2874 -156.7032 -159.1848 -161.7210 -164.3035
[232] -151.7728 -154.0259 -156.3804 -158.8141 -161.3119 -163.8627 -166.4585
[239] -153.8552 -156.1257 -158.4960 -160.9439 -163.4546 -166.0173 -168.6239
[246] -145.2535 -147.4591 -149.7679 -152.1590 -154.6172 -157.1316 -159.6938
[253] -147.0255 -149.3100 -151.6819 -154.1245 -156.6258 -159.1769 -161.7706
[260] -148.9374 -151.2712 -153.6843 -156.1621 -158.6938 -161.2713 -163.8883
[267] -150.9333 -153.3009 -155.7432 -158.2464 -160.8007 -163.3982 -166.0331
[274] -152.9829 -155.3752 -157.8393 -160.3620 -162.9336 -165.5468 -168.1959
[281] -155.0684 -157.4795 -159.9606 -162.4985 -165.0839 -167.7098 -170.3704
[288] -157.1781 -159.6042 -162.0987 -164.6489 -167.2457 -169.8818 -172.5520
[295] -148.5135 -150.8739 -153.3088 -155.8048 -158.3521 -160.9432 -163.5721
[302] -150.3975 -152.8160 -155.2986 -157.8347 -160.4161 -163.0367 -165.6913
[309] -152.3817 -154.8386 -157.3540 -159.9184 -162.5247 -165.1671 -167.8413
[316] -154.4282 -156.9125 -159.4519 -162.0375 -164.6627 -167.3221 -170.0115
[323] -156.5155 -159.0204 -161.5781 -164.1802 -166.8202 -169.4931 -172.1948
[330] -158.6301 -161.1510 -163.7232 -166.3385 -168.9905 -171.6744 -174.3862
[337] -160.7631 -163.2968 -165.8808 -168.5068 -171.1687 -173.8617 -176.5820
simulation - training - test
Code
multiple_test_res
Output
DoubleNegativeDroplets DoublePositiveDroplets WildtypeOnlyDroplets
1 7521 644 4889
2 8466 152 5252
MutantOnlyDroplets mutant_molecules_per_droplet
1 946 0.1006258337
2 130 0.0004839021
wildtype_molecules_per_droplet p_val test_statistic mutation_detected
1 0.5028811 0.0000000 3101.0031047 TRUE
2 0.4877604 0.6756611 0.1750512 FALSE
allele_frequency total_mutant_molecules total_wildtype_molecules
1 0.1667351811 1408.76167 7040.335
2 0.0009911067 6.77463 6828.645
mutant_molecules_per_droplet_CI_lower mutant_molecules_per_droplet_CI_upper
1 0.09300436 0.108582986
2 0.00000000 0.003658208
allele_frequency_CI_lower allele_frequency_CI_upper
1 0.1560776 0.177578689
2 0.0000000 0.007444179
total_mutant_molecules_CI_lower total_mutant_molecules_CI_upper
1 1302.061 1520.16181
2 0.000 51.21491
wildtype_molecules_per_droplet_CI_lower
1 0.4854383
2 0.4706541
wildtype_molecules_per_droplet_CI_upper
1 0.5207539
2 0.5052932
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