mhg: Non-parametric rank enrichment test for binary data.

Description Details References

Description

This package implements a non-parametric enrichment test for ranked binary lists. This is a general package suitable for many applications. For example, it can be used for gene-set enrichment tests to find enrichment for gene annotations.

Details

Run the test with mhg_test

Plot the results with plot_mhg

References

Eden, E., Lipson, D., Yogev, S. & Yakhini, Z. Discovering motifs in ranked lists of DNA sequences. PLoS Comput. Biol. 3, e39 (2007). http://dx.doi.org/10.1371/journal.pcbi.0030039

Wagner, F. GO-PCA: An Unsupervised Method to Explore Biological Heterogeneity Based on Gene Expression and Prior Knowledge. bioRxiv (2015). http://dx.doi.org/10.1101/018705


slowkow/mhg documentation built on May 30, 2019, 3:06 a.m.