Description Details References
This package implements a non-parametric enrichment test for ranked binary lists. This is a general package suitable for many applications. For example, it can be used for gene-set enrichment tests to find enrichment for gene annotations.
Run the test with mhg_test
Plot the results with plot_mhg
Eden, E., Lipson, D., Yogev, S. & Yakhini, Z. Discovering motifs in ranked lists of DNA sequences. PLoS Comput. Biol. 3, e39 (2007). http://dx.doi.org/10.1371/journal.pcbi.0030039
Wagner, F. GO-PCA: An Unsupervised Method to Explore Biological Heterogeneity Based on Gene Expression and Prior Knowledge. bioRxiv (2015). http://dx.doi.org/10.1101/018705
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