A package for cross-validated adaptive enrichment signature design (CADEN). The package provides three main funcitons: ‘simulate_data’ ‘analyse_simdata’ and ‘analyse_realdata’. Additional function is ‘get_stage2’ for simulating a data set for stage 2 based on a data set from stage 2. simulate_data: The function simulates covariates data and binary responses for stage 2 to be used in the analysis of the CADEN design. analyse_simdata: The function computes the power of the design for the simulated data according to the CADEN design. analyse_realdata: The function analyses the real data according to the CADEN design.
library('devtools') install_github('svetlanache/caden')
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