#' A covariate data set.
#'
#' A dataset containing covariate information.
#'
#' @format A tibble with 12 rows and 4 variables:
#' \describe{
#' \item{ID}{Individual}
#' \item{TIME}{Time, in hours}
#' \item{VARIABLE}{Variable}
#' \item{VALUE}{Value of the variable}
#' }
"df_cov"
#' Starting covariate data set.
#'
#' A dataset containing covariate information.
#'
#' @format A data frame with 4 rows and 3 variables:
#' \describe{
#' \item{ID}{Individual}
#' \item{VARIABLE}{Variable}
#' \item{VALUE}{Value of the variable}
#' }
"df_cov_start"
#' A covariate data set to be used with time dependent covariates.
#'
#' A dataset containing time dependent covariates.
#'
#' @format A data frame with 6 rows and 4 variables:
#' \describe{
#' \item{ID}{Individual}
#' \item{VARIABLE}{Variable}
#' \item{VALUE}{Value of the variable}
#' \item{TIME}{Time, in hours}
#' }
"df_cov_time_dependent_start"
#' A dose data set.
#'
#' A dataset containing dose information.
#'
#' @format A data frame with 12 rows and 3 variables:
#' \describe{
#' \item{ID}{Individual}
#' \item{TIME}{Time, in weeks}
#' \item{AMT}{Dose, in mg}
#' }
"df_dose"
#' A dose data set including datetimes.
#'
#' A dataset containing dose information in datetime format.
#'
#' @format A data frame with 5 rows and 12 variables:
#' \describe{
#' \item{ID}{Individual}
#' \item{TRT}{Treatment label}
#' \item{DOSE}{Dose, in mg}
#' \item{PERIOD}{Period}
#' \item{DAY}{Day of adminsitration}
#' \item{AMT}{Dose, in mg}
#' \item{DATETIME}{Dta ein datetime format}
#' \item{TIMEPOINT}{Timepoint}
#' \item{COHORT}{Cohort}
#' \item{FORM}{Drug form}
#' \item{TREATMENT}{Treatment}
#' \item{FOOD}{Food status}
#' }
"df_dose_datetime"
#' A dose data set to be used with EVID=4.
#'
#' A dataset containing dosing information.
#'
#' @format A data frame with 418 rows and 10 variables:
#' \describe{
#' \item{ID}{Individual}
#' \item{PERIOD}{Period}
#' \item{TIMEPOINT}{Timepoint}
#' \item{TIME}{Time, in hours}
#' \item{AMT}{Dose, in mg}
#' \item{TRT}{Treatment label}
#' \item{DAY}{Day of adminsitration}
#' \item{SEQUENCE}{Sequence}
#' \item{TRT2}{Treatment}
#' \item{EVID}{Evid value}
#' }
"df_dose_evid4"
#' A dose data set to be used with optional columns.
#'
#' A dataset containing dosing information.
#'
#' @format A data frame with 4 rows and 6 variables:
#' \describe{
#' \item{ID}{Individual}
#' \item{TIME}{Time, in hours}
#' \item{AMT}{Dose, in mg}
#' \item{OCC}{Occasion}
#' \item{TIMEPOINT}{Timepoint}
#' \item{TRT}{Treatment}
#' }
"df_dose_optional_columns"
#' A dose data set example.
#'
#' A dataset containing dosing information.
#'
#' @format A data frame with 4 rows and 3 variables:
#' \describe{
#' \item{ID}{Individual}
#' \item{TIME}{Time, in hours}
#' \item{AMT}{Dose, in mg}
#' }
"df_dose_start"
#' An extra times data set example.
#'
#' A dataset containing extra times.
#'
#' @format A data frame with 251 rows and 1 variable:
#' \describe{
#' \item{TIME}{Time, in hours}
#' }
"df_extra_times"
#' An extra times data set example with datetime format.
#'
#' A dataset containing extra times in datetime format.
#'
#' @format A data frame with 20 rows and 1 variable:
#' \describe{
#' \item{ID}{Individual}
#' \item{DATETIME}{Datetime}
#' \item{TIMEPOINT}{Timepoint}
#' }
"df_extra_times_datetime"
#' An extra times metabolite data set to be used with EVID=4.
#'
#' A dataset containing extra times for an hypothetical metabolite.
#'
#' @format A data frame with 770 rows and 3 variable:
#' \describe{
#' \item{PERIOD}{Period}
#' \item{TIMEPOINT}{Timepoint}
#' \item{TIME}{Time, in hours}
#' }
"df_extra_times_metabolite_evid4"
#' An extra times parent data set to be used with EVID=4.
#'
#' A dataset containing extra times for an hypothetical parent drug.
#'
#' @format A data frame with 770 rows and 3 variable:
#' \describe{
#' \item{PERIOD}{Period}
#' \item{TIMEPOINT}{Timepoint}
#' \item{TIME}{Time, in hours}
#' }
"df_extra_times_parent_evid4"
#' An extra times data set example.
#'
#' A dataset containing extra times.
#'
#' @format A data frame with 1040 rows and 3 variable:
#' \describe{
#' \item{ID}{Individual}
#' \item{TIME}{Time, in hours}
#' \item{TIMEPOINT}{Timepoint}
#' }
"df_extra_times_time"
#' A pharmacokinetic metabolite data set to be used with EVID=4.
#'
#' A dataset containing pharmacokinetic information for an hypothetical metabolite.
#'
#' @format A data frame with 1359 rows and 7 variables:
#' \describe{
#' \item{ID}{Individual}
#' \item{PERIOD}{Period}
#' \item{TIMEPOINT}{Timepoint}
#' \item{TIME}{Time, in hours}
#' \item{DV}{Drug concentration, in mg/L}
#' \item{TIMEDAY}{Timeday}
#' \item{DAY}{Day of adminsitration}
#' }
"df_metabolite_evid4"
#' A pharmacokinetic parent data set to be used with EVID=4.
#'
#' A dataset containing pharmacokinetic information for an hypothetical parent drug.
#'
#' @format A data frame with 1359 rows and 7 variables:
#' \describe{
#' \item{ID}{Individual}
#' \item{PERIOD}{Period}
#' \item{TIMEPOINT}{Timepoint}
#' \item{TIME}{Time, in hours}
#' \item{DV}{Drug concentration, in mg/L}
#' \item{TIMEDAY}{Timeday}
#' \item{DAY}{Day of adminsitration}
#' }
"df_parent_evid4"
#' An starting pharmacoynamic data set example.
#'
#' A dataset containing pharmacodynamic observations.
#'
#' @format A tibble with 6 rows and 3 variable:
#' \describe{
#' \item{ID}{Individual}
#' \item{TIME}{Time, in hours}
#' \item{DV}{Response, ng/mL}
#' }
"df_pd_start"
#' A pharmacokinetic data set example.
#'
#' A dataset containing pharmacokinetic information.
#'
#' @format A tibble with 12 rows and 3 variable:
#' \describe{
#' \item{ID}{Individual}
#' \item{TIME}{Time, in hours}
#' \item{DV}{Response, ng/mL}
#' }
"df_pk_start"
#' A pharmacokinetic data set example in datetime format.
#'
#' A dataset containing pharmacokinetic information.
#'
#' @format A data frame with 65 rows and 7 variable:
#' \describe{
#' \item{ID}{Individual}
#' \item{DV}{Response, ng/mL}
#' \item{DATETIME}{Datetime}
#' \item{TIMEPOINT}{Timepoint}
#' \item{DAY}{Day}
#' \item{PERIOD}{Period}
#' \item{BLQ}{I a BLQ?}
#' \item{LLOQ}{Lower limit of quantification, ng/mL}
#' }
"df_pk_datetime"
#' A pharmacokinetic data set of metabolite data.
#'
#' A dataset containing pharmacokinetic information for an hypothetical metabolite.
#'
#' @format A data frame with 10 rows and 3 variable:
#' \describe{
#' \item{ID}{Individual}
#' \item{TIME}{Time, in hours}
#' \item{DV}{Drug concentration, ng/mL}
#' }
"df_pk_metabolite"
#' A pharmacokinetic data set to be used with optional columns.
#'
#' A dataset containing pharmacokinetic information.
#'
#' @format A data frame with 12 rows and 5 variable:
#' \describe{
#' \item{ID}{Individual}
#' \item{TIME}{Time, in hours}
#' \item{DV}{Drug concentration, ng/mL}
#' \item{OCC}{Occasion}
#' \item{TIMEPOINT}{Timepoint}
#' }
"df_pk_optional_columns"
#' A pharmacokinetic data set for an hypothetical parent drug.
#'
#' A dataset containing pharmacokinetic information.
#'
#' @format A data frame with 12 rows and 3 variable:
#' \describe{
#' \item{ID}{Individual}
#' \item{TIME}{Time, in hours}
#' \item{DV}{Drug concentration, ng/mL}
#' }
"df_pk_parent"
#' A pharmacokinetic data set.
#'
#' A dataset containing pharmacokinetic information.
#'
#' @format A tibble with 132 rows and 4 variable:
#' \describe{
#' \item{ID}{Individual}
#' \item{TIMEPOINT}{Timepoint}
#' \item{TIME}{Time, in hours}
#' \item{DV}{Drug concentration, ng/mL}
#' }
"df_pk"
#' An starting pharmacokinetic data set.
#'
#' A dataset containing pharmacokinetic information.
#'
#' @format A data frame with 12 rows and 3 variable:
#' \describe{
#' \item{ID}{Individual}
#' \item{TIME}{Time, in hours}
#' \item{DV}{Drug concentration, ng/mL}
#' }
"df_pk_start"
#' A pharmacodynamic data set.
#'
#' A dataset containing pharmacodynamic information for response 1.
#'
#' @format A data frame with 6 rows and 3 variable:
#' \describe{
#' \item{ID}{Individual}
#' \item{TIME}{Time, in hours}
#' \item{DV}{Response, ng/mL}
#' }
"df_response1"
#' A pharmacodynamic data set.
#'
#' A dataset containing pharmacodynamic information for response 2.
#'
#' @format A data frame with 6 rows and 3 variable:
#' \describe{
#' \item{ID}{Individual}
#' \item{TIME}{Time, in hours}
#' \item{DV}{Response, seconds}
#' }
"df_response2"
#' A pharmacodynamic data set.
#'
#' A dataset containing pharmacodynamic information for response 3.
#'
#' @format A data frame with 6 rows and 3 variable:
#' \describe{
#' \item{ID}{Individual}
#' \item{TIME}{Time, in hours}
#' \item{DV}{Response, in hours}
#' }
"df_response3"
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