R/data.R

#' Human DoRothEA
#'
#' A table reporting signed human TF-target interactions. This database covers
#'   in total 1395 TFs targeting 20,244 genes with 486,676 unique interactions.
#'   In addition, each TF is accompanied with an emperical confidence level that
#'   was derived from the number of supporting evidences for this
#'   TF/interaction. The range is from A (high quality) to E (low quality).
#'
#'
#' @format A table of human TF-target interactions:
#' \describe{
#'     \item{tf}{TF identifier as HGNC symbols}
#'     \item{confidence}{Summary confidence score classifying regulons based on
#'         their quality}
#'     \item{target}{target identifier as HGNC symbols}
#'     \item{mor}{mode of regulation indicating the effect of a TF on the
#'         target}
#' }
#'
#' @keywords datasets
#' @name dorothea_hs
#' @source \url{https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6673718/}
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#' Mouse DoRothEA
#'
#' A table reporting signed human TF-target interactions. This database covers
#'   in total 1179 TFs targeting 17,410 genes with 410,455 unique interactions.
#'   In addition, each TF is accompanied with an emperical confidence level that
#'   was derived from the number of supporting evidences for this
#'   TF/interaction. The range is from A (high quality) to E (low quality).
#'
#'
#' @format A table of mouse TF-target interactions:
#' \describe{
#'     \item{tf}{TF identifier as MGI symbols}
#'     \item{confidence}{summary confidence score classifying regulons based on
#'         their quality}
#'     \item{target}{target identifier as MGI symbols}
#'     \item{mor}{mode of regulation indicating the effect of a TF on the
#'         target}
#' }
#'
#' @keywords datasets
#' @name dorothea_mm
#' @source \url{https://www.ncbi.nlm.nih.gov/pubmed/31525460}
NULL

#' Entire database with associated meta data
#'
#' This table lists all human TF-target interactions that were derived from the
#'   four lines of evidences. Each interaction is assigned a confidence score
#'   based on the number of supporting evidences. The table provides also all
#'   required information to trace back the origin of the interaction.
#'
#'
#' @keywords datasets
#' @name entire_database
#' @source \url{https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6673718/}
NULL
t-stei/dorothea documentation built on March 19, 2022, 7:26 a.m.